The elastic strain/stress fields (halo) around a compressed amorphous nano-track (core) caused by a single high-energy ion impact on LiNbO3 are calculated. A method is developed to approximately account for the effects of crystal anisotropy of LiNbO3 (symmetry 3m) on the stress fields for tracks oriented along the crystal axes (X, Y or Z). It only considers the zero-order (axial) harmonic contr...

A fast 50 microm-accuracy alignment procedure has been developed for the radiosurgery of brain lesions in rats, using microbeam radiation therapy. In vivo imaging was performed using the pink beam (35-60 keV) produced by the ID17 wiggler at the ESRF opened at 120 mm and filtered. A graphical user interface has been developed in order to define the irradiation field size and to position the targ...

Survival and unscheduled DNA synthesis (UDS) were measured in a cultured insect cell line, TN-368, and a cultured mammalian cell line, V-79-4, following exposure to several fluences of ultraviolet light. TN-368 cells were approximately seven times more resistant to the lethal effects of UV than V-79 cells, as determined by colony formation. The amount of UDS per unit amount of DNA is about the ...

Ionizing radiation at low LET is more effective in the presence of oxygen than in its absence in producing most biological effects. Most experimental radiobiological irradiations are conducted in the presence of oxygen at sufficient concentration to produce a “full oxygen effect”. To understand the full oxygen effect it is helpful to review the traditional definition of OER, which is the ratio ...

Metal catalyzed cross-coupling reactions have been the preferred tools to access to modified nucleosides (on the C5-position of pyrimidines and on the C7- or C8-positions of purines). Our objective is to focus this mini-review on the Suzuki-Miyaura and on the Heck cross-couplings of nucleosides using microwave irradiations which is an alternative technology compatible with green chemistry and s...

Introduction Total body irradiations (TBI) for conditioning patients with leukemia prior to bone marrow transplantation (BMT) require time consuming verification of shielding block positions as well as dosimetric control. Short treatment times contribute to reproducibility and patient comfort and increase the accelerator capacity. To reduce setup time conventional port films were replaced by a ...

From cellular radiosensitivity parameters and theoretical particle-energy spectra in tissue, of the secondary particles from neutron and negative pion irradiations, RBE-Dose relations have been calculated. The theoretical results are compared with clinical and radiobiological data for normal tissue, tumours and cells in culture. Formulae for calculation, cellular parameters and the needed prope...

A 49-year-old female, who had undergone irradiation at six years of age as a treatment for a cutaneous nasal hemangioma, developed later a devastating basal cell carcinoma requiring sub-amputation of the nose and subsequent reconstruction with a pre-expanded forehead flap. Basal cell carcinomas are now frequently reported as late sequelae of previous low-dose irradiations after 10-20 years, and...

The relative populations of two amino-hydroxy conformers of cytosine, differing in rotation of the OH group by approximately 180 degrees , were selectively and repeatedly manipulated with narrowband, near-infrared laser light. For cytosine monomers isolated in a low-temperature Ar matrix, laser irradiations at 7013 cm(-1) and at 7034 cm(-1) were found to induce effective transformations of the ...