A wide assortment of antibodies has been analysed by qualitative and quantitative techniques for their content of group I- and group II-type gamma-globulin molecules. These included Rh antibodies, isoagglutinins, thyroglobulin antibodies, dextran antibodies, and teichoic acid antibodies. All the antibodies studied showed the presence of both groups. However, the ratio of the two varied widely i...

Investigation of desertification trend needs understanding of phenomena creating changes singly or action and reaction together in the manner that these changes were ended up in land degradation. In investigation of pedological criterion onland degradation in Quaternary rock units, first, a part of the Rude-Shoor watershed area was selected. After distinguishing target area, maps of slope class...

The host-pathogen relationship is the focus of many different studies which use a variety of disease models and different pathogens. Immunological studies in the mouse using the intracellular parasite Leishmania have helped define several aspects of host-pathogen interactions. Resistance to Leishmania is dependent on the development of CD4+ Th1 cells which promote an effective cell mediated imm...

We present the study of radiative tau decay ($\tau^- \rightarrow \pi^- \nu_\tau \gamma$), computing structure dependent contribution using Light Cone Sum Rules. This includes same form factors as pion with crucial difference that momentum transfer squared, $t$, between pion-photon system is positive, which makes these timelike and also $t$ can now take values upto $m_\tau^2$ , it produce real h...

Interferons (IFNs) comprise a family of polypeptides that exhibit diverse biological effects such as inhibition of cell growth and protection against viral infection. These activities are based mainly on the transcriptional induction of cellular genes by both type I (IFN-alpha and IFN-beta) and type II (IFN-gamma) interferons. Several of these IFN-induced early response genes have been cloned a...

In the human breast cancer cell line MCF-7, the nucleotides ATP gamma S and UTP, acting extracellularly through the purinergic receptor P2Y(2), lead to elevated intracellular calcium levels and increased proliferation. ATP gamma S and UTP treatment of MCF-7 cells activated transcription of the immediate early gene c-fos, an important component in the response to proliferative stimulation. c-fos...

The ability of Toxoplasma gondii to evade the host immune response during primary infection in humans is poorly understood. In murine toxoplasmosis, infected spleen macrophages release soluble factors that mediate a transient immunosuppression, which may allow the parasite to become established. When an enriched population of human monocytes from seronegative individuals was incubated with toxo...

A graph $Gamma$ is said to be vertex-transitive or edge‎- ‎transitive‎ ‎if the automorphism group of $Gamma$ acts transitively on $V(Gamma)$ or $E(Gamma)$‎, ‎respectively‎. ‎Let $Gamma=Cay(G,S)$ be a Cayley graph on $G$ relative to $S$‎. ‎Then, $Gamma$ is said to be normal edge-transitive‎, ‎if $N_{Aut(Gamma)}(G)$ acts transitively on edges‎. ‎In this paper‎, ‎the eigenvalues of normal edge-tra...

Human umbilical vein endothelial cells grown in vitro under standard conditions contain a high level of mRNA specific for the complement regulatory factors H and I. An additional 1.8-kb mRNA encoding a truncated form of factor H is also present. IFN-gamma stimulation of the cells causes a 6-7 fold increase in both factor H mRNA species, and a greater than 10-fold increase in factor I mRNA. IL-1...

The importance of PLC activation in cell proliferation is evident from the fact that the hydrolysis of PtdIns(4,5)P2 is one of the early events that follow the interaction of many growth factors and mitogens with their respective receptors. However, the importance of PLC activation is not restricted to proliferation; it is one of the most common transmembrane signaling events elicited by recept...