Gibberellic acid (GA3) is a group of plant hormones identified in various plants. The aim of this study was to determine the effects of GA3 on sperm parameters and in vitro fertilization (IVF). Fifty six adult male rats were divided into seven groups as, control, treatment and sham. Following 15, 30 and 45 days of GA3 and methanol alcohol (MA) administration, rats were euthanized and epididymis...

The present study was carried out to evaluate the specific and amplified β-glucuronidase (βG) expression in prostate cancer cells by using a prostate‑specific antigen (PSA) promoter-controlled bicistronic adenovirus and to evaluate the specific killing of prostate cancer cells after the application of the prodrug DOX‑GA3. Bicistronic adenoviral expression vectors were constructed, and the effec...

Objectives The objective of this study was to evaluate the ability of the stroke volume (SV) variation with 250 ml (Δ250SV) of volume expansion (VE) to predict further SV increase with VE. We also studied the ability of respiratory SV variation (ΔrespSV) to discriminate fluid responisvenness according to the amount of VE (250 then 500 ml). Fluid expansion consisted on infusion of 500 ml of Ring...

Cereal aleurone responses to gibberellic acid (GA3) include activation of synthesis of hydrolytic enzymes and acidification of the external medium. We have studied the effect of the pH of the incubation medium on the response of wheat (Triticum aestivum) aleurone cells to GA3. De-embryonated half grains show the capacity for GA3-activated medium acidification when incubation is carried out at p...

Carica papaya (papaya) seed germinate readily fresh from the fruit, but desiccation induces a dormant state. Dormancy can be released by exposure of the hydrated seed to a pulse of elevated temperature, typical of that encountered in its tropical habitat. Carica papaya is one of only a few species known to germinate in response to heat shock (HS) and we know little of the mechanisms that contro...

The function of monoacylglycerol lipase (MGL), a key actor in the hydrolytic deactivation of the endocannabinoid 2-arachidonoyl-sn-glycerol (2AG), is tightly controlled by the cell's redox state: oxidative signals such as hydrogen peroxide suppress MGL activity in a reversible manner through sulfenylation of the peroxidatic cysteines, C201 and C208. Here, using as a starting point the crystal s...

background & aim: lemon verbena (lippia citriodora h.b.k.) is a richly scented herb and has a long history as a sacred and medicinal plant. select an appropriate medium in tissue culture is a necessity for success experimental: to evaluate the effect of 10 medium of previous researches for lippia micropropagation (1- ms medium supplemented with bap (3 mgl-1) + iba (0.1 mgl-1) + activated ch...

Plant growth in a controlled environment system is highly dependent on the availability of light. The light-emitting diode (LED) capable providing needed quality and quantity light for plant. purpose this study was to determine effect white LED intensity vitro propagated apple (M-9) seedlings system. Seedlings were grown 30 days under five different intensities: 100–500 (L1), 250–500 (L2), 500–...

BACKGROUND This double-blind, multicenter, placebo-controlled study determined the efficacy and safety of dofetilide in converting atrial fibrillation (AF) or atrial flutter (AFl) to sinus rhythm (SR) and maintaining SR for 1 year. METHODS AND RESULTS Patients with AF or AFl (n=325) were randomized to 125, 250, or 500 microgram dofetilide or placebo twice daily. Dosages were adjusted for QTc ...

the current study dealt with the interaction of garlic homogenate (gh) with propranolol (pro) in rat, and to determine whether this effect is associated with biochemical and histological changes. albino rats were treated with gh at three different doses of 125 mg/kg (gh-125), 250 mg/kg (gh-250) and 500 mg/kg (gh-500) orally for 30 days and pro was incorporated in the interactive groups during t...