Acrylamide (AA) is a suspected human carcinogen generated in carbohydrate-rich foodstuffs upon heating. Glycidamide (GA), formed via epoxidation, presumably mediated by cytochrome P450 2E1, is thought to be the active metabolite playing a central role in AA genotoxicity. In this work we investigated DNA damage induced by AA and GA in mammalian cells, using V79 Chinese hamster cells. For this pu...

SWI/SNF chromatin remodeling complexes perform a pivotal function in the regulation of eukaryotic gene expression. Arabidopsis (Arabidopsis thaliana) mutants in major SWI/SNF subunits display embryo-lethal or dwarf phenotypes, indicating their critical role in molecular pathways controlling development and growth. As gibberellins (GA) are major positive regulators of plant growth, we wanted to ...

Bioactive gibberellins (GAs) control many aspects of growth and development in plants. GA(1) has been the most frequently found bioactive GA in various tissues of flowering plants, but the enzymes responsible for GA(1) biosynthesis have not been fully elucidated due to the enzymes catalyzing the 13-hydroxylation step not being identified. Because of the lack of mutants defective in this enzyme,...

background bipolar disorder is a biological brain disorder which is associated with debilitating fluctuation in mood and adverse effects on patients, their families and society. the importance of genetics and its role in bipolar disorder is a controversial issue to discuss. evidence indicates a relation between the risk of bipolar disorder and specific genes. amongst the genes whose role has be...

Field trials with Ficus benjamina L.were conducted at the experimental farm of Faculty of Agriculture, University Azad Jiroft in 2012 growth seasons. The aim of this work is to study the effect of foliar application with gibberellic acid (GA3) and benzyladenine (BA) at 0, 100 and 200 mg.L-1 on the vegetative growth and Photosynthetic pigments of Ficus benjamin...

The plant hormone gibberellin (GA) regulates major aspects of plant growth and development. The role of GA in determining plant stature had major impacts on agriculture in the 1960s, and the development of semi-dwarf varieties that show altered GA responses contributed to a huge increase in grain yields during the 'green revolution'. The past decade has brought great progress in understanding t...

Genetic Algorithm (GA) is known as method to solve Traveling Salesman Problem (TSP). However, GA needs amount of time for finding approximate solution. Thus, this study proposes Genetic Algorithm with Virus Infection (GAVI). GAVI algorithm is using Virus Theory of Evolution (VTE) to be based on Genetic Algorithm (GA). GA can evolve by natural selection, while VTE can evolve by virus infection. ...

In this paper a new method is proposed based on the combination of ICA (Imperial Competitive Algorithm) and GA (Genetic Algorithm) which improves the convergence speed and accuracy of the optimization results. The new algorithm, which is named R-ICA-GA (RecursiveICA-GA), runs ICA and GA consecutively. It is shown that a fast decrease occurs while the proposed algorithm switches from ICA to GA. ...

To understand the mechanism by which light regulates a gibberellin (GA)-insensitive gene in DongJinByeo (Oryza sativa cv DongJin), both green and etiolated DongJinByeo seedlings were submerged in water and treated with GA. Total RNA from the seedlings was isolated and hybridized with cDNA of a GA-insensitive gene homolog. The amount of transcript for the GA-insensitive gene homolog was higher i...

In Vitro Fertilization Genetic Algorithm (IVF/GA) is a recently created algorithm that combine the concepts of Genetic Algorithm and In Vitro Fertilization. The IVF/GA has the aim to improve the performance of Genetic Algorithm with the addition of IVF-Inspired mechanisms that better exploit the information of individuals. The Multimensional Knapsack Problem (MKP) is a complex combinatorial pro...