نتایج جستجو برای: g polymorphism

تعداد نتایج: 537054  

2012
Jung-Hwa Ryu Seung-Jung Kim

BACKGROUND/AIMS Chronic inflammatory status is a possible risk factor for vascular access dysfunction in hemodialysis (HD) patients, but susceptibility differences appear among individuals. Interleukin (IL)-6 is a well-known inflammatory cytokine with various polymorphisms. We examined whether IL-6 polymorphisms are associated with vascular access dysfunction in HD patients. METHODS A total o...

2013
Ewelina Synowiec Katarzyna A. Wojcik Justyna Izdebska Ewelina Binczyk Janusz Blasiak Jerzy Szaflik Jacek P. Szaflik

PURPOSE We investigated the association between genotypes and haplotypes of the c.-61G>T (rs 1801320) and c.-98G>C (rs 1801321) polymorphisms of the RAD51 gene and the occurrence of keratoconus (KC) and Fuchs endothelial corneal dystrophy (FECD) in dependence on some environmental factors. METHODS The polymorphisms were genotyped in peripheral blood lymphocytes of 100 KC and 100 FECD patients...

2015
Linguo Xie Yan Sun Tao Chen Dawei Tian Yujuan Li Yu Zhang Na Ding Zhonghua Shen Hao Xu Xuewu Nian Nan Sha Ruifa Han Hailong Hu Changli Wu

OBJECTIVE Human murine double minute 2 protein (MDM2) is mainly a negative regulator of p53 tumor suppressor pathway. We aimed to investigate the association between MDM2 SNP309 polymorphism and bladder cancer risk. METHODS A total of 535 bladder cancer patients and 649 health controls were recruited for our study. MDM2 SNP309 T>G polymorphism was genotyped by polymerase chain reaction-ligase...

2009
Kanjana Suriyaprom Benjaluck Phonrat Pisit Namjuntra Siriporn Chanchay Rungsunn Tungtrongchitr

The prevalence of type 2 diabetes has been increased in Thais. Resistin is an adipokine that involve in glucose homeostasis and is a candidate gene for type 2 diabetes. We performed a case-control study in representative sample of 200 Thai volunteers, 105 controls and 95 type 2 diabetes subjects. The purposes of the present study were to investigate the association between two SNPs (single nucl...

Journal: :jundishapur journal of microbiology 0
mehrdad hajilooi department of immunology, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran pegah lotfi department of microbiology, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran farhad seif department of immunology and microbiology, faculty of medicine, shahrekord university of medical sciences, shahrekord, ir iran ahad bazmani infectious and tropical diseases research center, tabriz university of medical sciences, tabriz, ir iran mohammad momeni department of immunology, school of public health, tehran university of medical sciences, tehran, ir iran ali ravary occupational environment research center, rafsanjan university of medical sciences, rafsanjan, ir iran

conclusions according to the results, the polymorphisms within the +49 position of ctla-4 can be associated with vl and may be considered as risk factors for the disease. results our results indicated that both ctla-4 +49a/g polymorphisms were significantly associated with vl. materials and methods in this cross-sectional study, 88 patients with clinical presentations of vl, who were seropositi...

Journal: :KnE Life Sciences 2022

Melanocortin-4 Receptor (MC4R) expressed in hypothalamus which is part of the brain that are involved regulation appetite, metabolism and bodyweight. This study aimed to identify MC4R gene diversity second cross generation Belgian Blue, Wagyu, Brahman crossbred its relationship with body weight size birth. Polymerase Chain Reaction (PCR) DNA sequencing were used Single Nucleotide Polymorphism (...

Amir Hassan Zarnani Farah Idali Mahmood Jeddi-Tehrani, Motahareh Bahadori Omid Zarei Reza Hadavi Saeed Zarei

Background: Pro-inflammatory and anti-inflammatory cytokines and polymorphisms of their genes have been described to be involved in the pathogenesis of recurrent miscarriage (RM). Objective: To investigate the association between RM and five polymorphisms of cytokine genes, interleukin 10 (IL-10), (-592 A/C, -819 C/T, -1082 A/G), IL-6 (-174 C/G) and IL-17 (-197 G/A) in Iranian women. Method: Po...

Journal: :iranian journal of applied animal science 2012
l.c.m. armeiro r.a. curi l.a.l. chardulo j.n.p. puoli filho m.d. silveira da mota

the aims of the present study were to propose apolymerase chain reaction-restriction fragment length polymorphismpcr-rflp genotyping method for the ay_376689:c.773c>t single nucleotide polymorphism snp of the equine prkag3 gene, related to muscle performance, as well as to characterize this snp and a second polymorphism, aawr_02017454:g.121684t>c of the spata1 gene, related to male fertility, i...

2017
Danial Jahantigh Abasalt Hosseinzadeh Colagar

We evaluate the association between genetic polymorphisms of XRCC5 VNTR, XRCC6 -61C>G, and XRCC7 6721G>T with male infertility susceptibility. A total of 392 men including 178 infertile males (102 idiopathic azoospermia and 76 severe oligozoospermia) and 214 healthy controls were recruited. XRCC6 -61C>G and XRCC7 6721G>T genotyping was performed by PCR-RFLP whereas XRCC5 VNTR was performed by P...

Journal: :Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2014
Luyao Chen Shushan Zhao Guangjie Cheng Ruizheng Shi Guogang Zhang

OBJECTIVE To assess the association between myeloperoxidase (MPO) gene polymorphism and coronary artery disease (CAD). METHODS Several databases were used to retrieve relevant literature up to March 2013 by keywords. A Meta-analysis was performed by Stata12.0 software to estimate the pooled odds ratio (OR) and the 95% confidence interval (CI). Heterogeneity among studies was tested and sensit...

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