We explore online inductive transfer learning, with a feature representation from radial basis function network formed of Gaussian mixture model hidden processing units to direct, recurrent reinforcement learning agent. This agent is put work in an experiment, trading the major spot market currency pairs, where we accurately account for transaction and funding costs. These sources profit loss, ...

Prothrombin complex concentrates (PCCs) are widely administered for emergency oral anticoagulation reversal and for coagulation defects in liver disease. Pharmacokinetic data may help to optimize treatment. The objective of this study was to characterize the pharmacokinetics of a PCC (Beriplex P/N) containing coagulation factors II (FII), VII (FVII), IX (FIX) and X (FX) and anticoagulant protei...

The expression of a number of blood coagulation factors (F) (FX, FIX, FVIII, FVII, alpha-, beta-, gamma-fibrinogen chains, protein C, and antithrombin III [AT III]) was analyzed at RNA and protein level in 5- to 10-week-old human embryos and fetuses. FX, FIX, and FVII were also analyzed at protein level. Total and poly(A)+ RNA, extracted from embryonic-fetal (FL) and adult liver (AL), were anal...

OBJECTIVE We sought to develop and provide preliminary validation for a questionnaire evaluating functioning related to ADHD (i.e., the FX-II) with a particularly underserved group (i.e., Mexican youth). METHOD 191 Mexican raters completed the FX-II alongside measures of ADHD symptoms, impairment, cultural values, and demographics: 127 raters were caregivers of treatment-naïve youth (i.e., co...

Adenosis occurred in transplanted C57BL and BALB/c mice Müllerian-derived reproductive tract regions, cervix, and/or fornix (FX), and middle vagina but never in the urogenital sinus-derived portion of the vagina, after a 1-mo exposure to endogenous ovarian hormones or exogenous estradiol (E2). Grafts in ovariectomized hosts did not exhibit adenosis, confirming its dependence on estrogen. C57BL ...

Fucoxanthin (FX) is a natural carotenoid with reported antitumorigenic activity. This study explored the effects of FX and its deacetylated product, fucoxanthinol (FXOH), on B-cell malignancies, including Burkitt's lymphoma, Hodgkin's lymphoma and Epstein-Barr virus-immortalized B cells. Both FX and FXOH reduced the viability of these malignant B ...

We derive the second and most stringent limit to date of the X-ray/radio flux ratio (FX/F1.4GHz) for the radio bursts associated with the recently identified source class, the Rotating Radio Transients (RRATs). We analyze 20.1 hr of RXTE/PCA observations of RRAT J1819−1458 – a period during which 350±23 RRAT radio bursts occurred, based on the previously observed average radio burst rate. No X-...

We develop a zero-delay hidden Markov model (HMM) to capture the evolution of multivariate foreign exchange (FX) rate data under a frequent trading environment. Recursive filters for the Markov chain and pertinent quantities are derived, and subsequently employed to obtain estimates for model parameters. The rationale of zero-delay HMM hinges on the idea that with fast trading, available inform...

Suppose that the integers are assigned i.i.d. random variables f! x g (taking values in the unit interval), which serve as an environment. This environment deenes a random walk fX n g (called a RWRE) which, when at x, moves one step to the right with probability ! x , and one step to the left with probability 1 ? ! x. Solomon (1975) determined the almost-sure asymptotic speed v (=rate of escape...

Drugs which influence 5-HTergic mechanisms can modify neuroleptic-induced catalepsy (NC) in rodents, a phenomenon produced by striatal dopamine (DA) receptor blockade. Previous research also suggests a role for endogenous nitric oxide (NO) in the modulation of striatal DAergic neurotransmission; in addition, NO seems to play a role in the 5-HT reuptake mechanism. It is known that clomipramine p...