An understanding of three-dimensional structure/function relationships is increasingly important to modern biochemistry and molecular biology. Not only are the overall “folds” that illuminate evolutionary relationships uncompromisingly three-dimensional but so, too, are the critical details at active sites. Fortunately, most protein and nucleic acid structures are now readily available on the I...

An understanding of three-dimensional structure/function relationships is increasingly important to modern biochemistry and molecular biology. Not only are the overall “folds” that illuminate evolutionary relationships uncompromisingly three-dimensional but so, too, are the critical details at active sites. Fortunately, most protein and nucleic acid structures are now readily available on the I...

We present a case of a 27-month-old boy with severe Clostridium difficile infection complicated by toxic megacolon, rectal prolapse, hypoalbuminemia, and ascites. The patient improved with antibiotics but later presented with recurrent Clostridium difficile colitis. Antibiotic therapy for recurrent Clostridium difficile infection was given and after recovery, fecal microbiota transplantation wa...

The elderly have long been considered the primary target group for improved cobalamin nutrition. Cobalamin insufficiency has been associated with a variety of neurodegenerative conditions in this demographic group (1). However, there is mounting evidence that cobalamin deficiency is also associated with neurodevelopmental morbidity during infancy (2). In a simple, welldesigned, randomized doubl...

A 33-month-old girl presented with 3 days of fever and 1 day of multiple paroxysmal episodes of screaming with apparent unresponsiveness, flexed lower extremities, clenched hands, and upward eye deviation. These events lasted seconds to a minute at a time and occurred only during sleep. She slept peacefully between episodes and was easily awakened. She had a history of mild speech delay and mil...

Feeding disorders of infants and toddlers have become more prevalent as diagnostic criteria and assessment are specialized, yet few longitudinal studies have been conducted to investigate the effectiveness of treatment. Infantile Anorexia (IA) is a specific feeding disorder that often emerges between 6 months and 3 years of age, characterized by the child’s refusal to eat adequate amounts of fo...

The Abridged Big Five-Dimensional Circumple~ (ABSC; Hofstee, de Raad, & Goldberg, 1992) was used to locate consensus across different conceptualizations of the "Big Five" or Five-Factor ModeL Trait rating data from instruments representing four different versions of the Big Five (Goldberg, 1992; Hogan & Johnson, 1981; McCrae & Costa, 1985; Norman, 1963) were subjected to separate ABSC analyses ...

In the literature it is still discussed whether teachers’ ICT training is in fact a critical factor for promoting technology integration in classrooms. For contributing to intensify the debate, a study was developed (a) to assess how teachers’ ICT training may or may not contribute to increase the level of ICT use in classrooms as well as teachers’ level of computers self-efficacy and (b) to id...

I've heard many women say that the day their child was born best of life, but it worst mine. After laboring for nearly forty hours, my body cut open and son pried from flesh. Earlier in day, his heartbeat had slowed to a dangerous rate while I pushing, still shook with epinephrine burned through veins recognition how fragile we both were, thin curtain between life death.His rebounded emergency ...

On the face of it, a psychologist is an odd choice for representative science; as psychologists, our scientific credentials are oft-disparaged, sometimes even by ourselves, only half-jokingly. But it turns out that work with which this particular cadre theologians has found meet to engage fits mostly within my disciplinary remit. Truly, in at least way, not grandparents’ science-and-religion, f...