background: introduction: searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. there are many biomarkers reported for neonatal sepsis. haptoglobin is an acute phase reactants which rise in response to infection and injuries. in this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...

We retrospectively reviewed the medical records of 284 patients with neutropenic fever following chemotherapy for acute leukemia at the Catholic Hematopoietic Stem Cell Transplantation Center from January 1998 to December 1999, to identify prognostic factors for infection-related mortality. Twenty-eight patients died of infections. There was no difference in median age, gender ratio, or underly...

BACKGROUND Invasive fungal infections are very severe infections associated with high mortality rates, despite the availability of new classes of antifungal agents. Based on pathophysiological mechanisms and limited pre-clinical and clinical data, adjunctive immune-stimulatory therapy with interferon-gamma (IFN-γ) may represent a promising candidate to improve outcome of invasive fungal infecti...

OBJECTIVE Infections remain an important complication of left ventricular assist device (LVAD) support. While relatively uncommon, fungal infections present a serious concern given a high association with adverse events including death. We sought to further characterize the epidemiology of fungemias during LVAD support. METHODS Retrospective review of 292 patients receiving LVAD support from ...

sepsis is one of the most important causes of mortality in trauma patients. sometimes its diagnosis could be difficult, especially at early stages. it is clear that early diagnosis of sepsis, especially with serum markers, may decrease the rate of death in trauma patients. investigation to find a rapid as well as accurate serum marker indicative of sepsis seems necessary. seum antithrombin iii ...

A growing population of immunosuppressed patients has resulted in increasingly frequent diagnoses of invasive fungal infections, including those caused by unusual yeasts. The incidence of non-albicans species of Candida is increasing compared with that of Candida albicans, and several species, such as Candida glabrata and Candida krusei, may be resistant to azole antifungal therapy. Trichosporo...

sepsis is the most common cause of neonatal mortality. as per national neonatal-perinatal database (nnpd), 2002-2003, the incidence of neonatal sepsis in india was 30 per 1000 live births. signs and symptoms of sepsis are nonspecific; therefore empirical antimicrobial therapy is promptly initiated after obtaining appropriate cultures. the early manifestations of neonatal sepsis are vague and il...

Background: Neonatal sepsis is a generalized bacterial infection which occurs in the first month of life. Intraventricular hemorrhage is the most common intracerebral disorder which occurs in premature neonates. Mean Platelet Volume (MPV) is considered as a marker of intraventricular hemorrhage (IVH) in some studies. The aim of this study was to evaluate the impact of MPV on IVH and sepsis in n...

cated for detection of invasive candidiasis. Our data indicate that the rate o f false positive results is potentially high in some patient collectives of risk; for example, after cardiac artery bypass grafting (CABG). Th e recently published guidelines from the Surviving Sepsis Campaign recommend the use of (13)-β-dglucan as a surrogate for invasive candidiasis [1]. Fung al infections are inc...