نتایج جستجو برای: fungal keratitis

تعداد نتایج: 57594  

2017
Jaspreet Kaur Jaswinder Singh Priyanka Mishra

Background & Objectives: Fungal infections of the eye are rampant in tropical regions and are responsible for significant ocular morbidity and blindness. Prompt and specific identification of fungi is important in order to define clinical treatment. However, in most cases conventional culture identification can be considered to be time consuming, of low sensitivity and not without errors. The a...

2018
Jing Zhong Lulu Peng Bowen Wang Henan Zhang Saiqun Li Ruhui Yang Yuqing Deng Haixiang Huang Jin Yuan

Purpose To investigate the expression and roles of type I and II interferons (IFNs) in fungal keratitis, as well as the therapeutic effects of tacrolimus (FK506) and voriconazole on this condition. Methods The mRNA and protein expression levels of type I (IFN-α/β) and II (IFN-γ) IFNs, as well as of related downstream inflammatory cytokines (interleukin (IL)-1α, IL-6, IL-12, and IL-17), were d...

شکوهی , دکتر طاهره ,

ABSTRACT Mycotic Keratitis, an important ophthalmologic problem, especially among the outdoor workers in the tropic regions, is frequently caused by filamentous fungi. Following trauma, a corneal ulcer developed in 3 male patients residing in rural areas of Sari. Traumatizing agents were likely paddy rice, soil and dust. Direct examination of all the corneal scrapings showed septate branched ...

2016
Jianzhang Hu Jingjin Zhang Yanling Li Xiaoli Han Weidong Zheng Juan Yang Guoxing Xu

Purpose. To evaluate the efficacy of a combination of intrastromal and intracameral injections of amphotericin B in the treatment of severe recalcitrant fungal keratitis. Methods. Patients with severe fungal keratitis who were resistant to conventional antifungal medical treatments and needed potential surgical intervention were recruited at the First Affiliated Hospital of Fujian Medical Unive...

2016
Cuiying Zhang Shufang Wei Liying Zhang Weijing Li Yan Lv Guoying Mu

To observe and analyze the curative effects of the treatment of riboflavin combined with 440 nm blue-light corneal cross-linking (CXL) treatment for fungal keratitis via a rabbit model experiment. A model of rabbit fungal keratitis was used through anterior stromal injection in which 24 rabbits were randomly divided into blank control, 360 nm group, and 440 nm group. Both groups underwent CXL t...

2015
Xinying You Jun Li Suxia Li Weiyun Shi

Purpose. To evaluate effects of lamellar keratectomy and intrastromal injection of 0.2% fluconazole (LKIIF) on fungal keratitis. Methods. Data for 54 eyes of consecutive patients with fungal keratitis treated with LKIIF were retrospectively analyzed. The lesions in these eyes did not heal or were aggravated after antifungal chemotherapy for 7 days. The maximum lesion diameters were ≤5 mm and ma...

2013
Sivagnanam Ananthi Namperumalsamy Venkatesh Prajna Prajna Lalitha Murugesan Valarnila Kuppamuthu Dharmalingam

Fusarium is the major causative agent of fungal infections leading to corneal ulcer (keratitis) in Southern India and other tropical countries. Keratitis caused by Fusarium is a difficult disease to treat unless antifungal therapy is initiated during the early stages of infection. In this study tear proteins were prepared from keratitis patients classified based on the duration of infection. Am...

Journal: :The British journal of ophthalmology 2003
Y-F Yao Y-M Zhang P Zhou B Zhang W-Y Qiu S C G Tseng

AIMS To investigate whether cryopreserved donor cornea could be used for therapeutic penetrating keratoplasty (PKP) to eradicate the infection, obviate complications, and preserve anatomical integrity in severe fungal keratitis. METHODS In this retrospective, consecutive case series, 45 eyes of 45 patients with severe fungal keratitis, which exhibited anterior chamber collapse, corneal perfor...

Journal: :Arquivos brasileiros de oftalmologia 2006
Gustavo Victor Milton Ruiz Alves Walton Nosé

The authors describe a case of fungal keratitis that the in vivo confocal microscopy helped in the diagnosis and follow-up. Confocal microscopy was done in a patient's ulcer that did not improve with several topical medicines. Corneal scrapings were obtained and culture results were without conclusion. We observed hyphae and infectious collections on confocal microscopy. New corneal culture sho...

Journal: :The British journal of ophthalmology 1975
R K Forster G Rebell

Medical treatment failure necessitated surgery in nine cases of fungal keratitis. Therapeutic surgery eliminated fungal infection in seven cases, and useful vision was retained in five out of six penetrating keratoplasties. In three cases Natamycin (Pimaricin) therapy rendered fungi non-viable, but two were demonstrable by histopathology. These results suggest that antifungal treatment should b...

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