PURPOSE Immunologic rejection is the most common cause of corneal allograft rejection. Ipsilateral ocular inflammation has been identified as a predictor of future corneal graft failure. This study investigates the effect of perioperative allergic conjunctivitis on corneal allograft survival. METHODS C57BL6 donor corneas were transplanted into naive A/J mice, A/J mice sensitized to short ragw...

PURPOSE To report a case of late iatrogenic bleb formation and hypotony maculopathy after pterygium surgery applying Mitomycin C (MMC). CASE REPORT A 66-year-old man presented with an elevated, bleb-like, fluid-filled, cystic lesion on the nasal sclera of the right eye. The patient had undergone pterygium surgery with a combination of conjunctival autograft and adjuvant intraoperative MMC 0.0...

PURPOSE To describe a new surgical approach for the tectonic reconstruction of the anterior ocular segment and the management of scleral and conjuctival melting. METHODS Case series of patients demonstrating anterior segment anomalies, such as scleral and conjunctival melting. The anterior stromal part of a pre-cut corneal graft for Descemet's stripping automated endothelial keratoplasty (DSA...

PURPOSE We sought to develop full-thickness ex vivo produced human conjunctiva and oral mucosa equivalents using a serum-free culture system without a feeder layer and to compare conjunctiva and oral mucosa equivalents to assess their suitability as graft materials for eyelid reconstruction. MATERIALS AND METHODS Human conjunctival and oral mucosal keratinocytes were cultured, expanded, and s...

background we present a novel method for augmenting the standard c-v flap used for nipple reconstruction with a free dermal graft which aims to improve the appearance of the nipple reconstruction, decrease loss of projection and improve patient satisfaction overall. methods the surgical technique for performing a free dermal graft augmentation of a cv flap is described. all patients who underwe...

Abstract Background Chronic ocular graft-versus-host disease (oGVHD) is an comorbidity of (GVHD) that usually occurs concurrently with systemic manifestations. Failure to detect and treat oGVHD in its early stages may lead progression signs symptoms leading refractory conventional treatment. Case presentation We report the clinical course a 19-year-old male 59-year-old female severe progressive...