نتایج جستجو برای: frag stats software and np

تعداد نتایج: 16860695  

2017
Qian Zhao

1 In multiple testing, weighted procedures are used for various reasons; for instance, (1) to increase power, (2) to incorporate previous knowledge about individual hypotheses, (3) to represent difference in importance (some hypotheses may be more important than others) or (4) to incorporate other measures of loss. The purpose of this question is to examine weighted procedures. Here, we assume ...

Journal: :Nature reviews. Molecular cell biology 2002
David E Levy J E Darnell

Extracellular proteins bound to cell-surface receptors can change nuclear gene expression patterns in minutes, with far-reaching consequences for development, cell growth and homeostasis. The signal transducer and activator of transcription (STAT) proteins are among the most well studied of the latent cytoplasmic signal-dependent transcription-factor pathways. In addition to several roles in no...

Journal: :Proceedings of the National Academy of Sciences 1996

Journal: :Tecciencia 2022

Utilization of solar energy for the fulfillment daily routine tasks has gained a lot interest in recent past. The complete utilization can be accomplished only if proper data is available particular site. measurement expensive and time consuming. Different empirical correlations are estimation radiations on In this research, monthly average radiation horizontal surface compared with measured as...

2011
Allen B. Downey

ion, 49 Adams, Cecil, 23 Adult Intelligence Scale, 44, 118 adult weight, 47, 48, 114 analysis, 49, 74, 88 anecdotal evidence, 2, 9 Anscombe’s quartet, 113 apparent effect, 8, 10, 20, 79 artifact, 8, 10 Australia, 37 average, 11, 68 bar plot, 15, 18 baseball, 61 basketball, 61 Bayes factor, 86 Bayes’s theorem, 63 Bayesian estimation, 77, 97, 104 Bayesian probability, 84, 86 Bayesianism, 54, 66, ...

1997
Christian Pape

In this paper we investigate the potential of interactive visualiza-tion for teaching the theory of NP-completeness to undergraduate students of computer science. Based on this analysis we developed some interactive Java applets which we use to present an NP-complete tiling problem PUZZLE in our lecture. This software is integrated into our hypertext lecture notes and our students also use it t...

2013
Charles E. Egwuagu Joseph Larkin, III

Signal transducers and activators of transcription (STATs) transduce extracellular signals that regulate the initiation, duration and intensity of immune responses. However, unbridled activation of STATs by pro-inflammatory cytokines or growth factors contributes to pathogenic autoimmunity. In this review, we briefly discuss STAT pathways that promote the development and expansion of T cells th...

Journal: :The Journal of Cell Biology 2006
Toshiyuki Kawashima Ying Chun Bao Yasushi Nomura Yuseok Moon Yukio Tonozuka Yukinori Minoshima Tomonori Hatori Akiho Tsuchiya Mari Kiyono Tetsuya Nosaka Hideaki Nakajima David A. Williams Toshio Kitamura

STAT transcription factors are tyrosine phosphorylated upon cytokine stimulation and enter the nucleus to activate target genes. We show that Rac1 and a GTPase-activating protein, MgcRacGAP, bind directly to p-STAT5A and are required to promote its nuclear translocation. Using permeabilized cells, we find that nuclear translocation of purified p-STAT5A is dependent on the addition of GTP-bound ...

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