نتایج جستجو برای: foxa2

تعداد نتایج: 549  

Journal: :Developmental biology 2010
Anabel Rojas William Schachterle Shan-Mei Xu Franz Martín Brian L Black

The embryonic endoderm is a multipotent progenitor cell population that gives rise to the epithelia of the digestive and respiratory tracts, the liver and the pancreas. Among the transcription factors that have been shown to be important for endoderm development and gut morphogenesis is GATA4. Despite the important role of GATA4 in endoderm development, its transcriptional regulation is not wel...

2017
Tong-Hong Wang Chi-Hao Wu Chau-Ting Yeh Shih-Chi Su Shih-Min Hsia Kung-Hao Liang Chin-Chuan Chen Chuen Hsueh Chi-Yuan Chen

Melatonin is the primary pineal hormone that relays light/dark cycle information to the circadian system. It was recently reported to exert intrinsic antitumor activity in various cancers. However, the regulatory mechanisms underlying the antitumor activity of melatonin are poorly understood. Moreover, a limited number of studies have addressed the role of melatonin in hepatocellular carcinoma ...

Journal: :Mechanisms of Development 2011
Xiaofang Xu Victoria L. Browning Jon S. Odorico

The study of how human embryonic stem cells (hESCs) differentiate into insulin-producing beta cells has twofold significance: first, it provides an in vitro model system for the study of human pancreatic development, and second, it serves as a platform for the ultimate production of beta cells for transplantation into patients with diabetes. The delineation of growth factor interactions regulat...

Journal: :Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2017

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