the aim of this paper is to develop a systematic method to analyze the effects of forming parameters on the quality of part formability and determine the optimal combination of the forming parameters for the sheet hydroforming process. in this paper, the effects of four important process parameters namely fluid pressure, friction coefficient at blank/punch interface, gap between die rim block a...

The Expanded Programme on Immunization (EPI) aims at the reduction of morbidity and mortality from vaccinepreventable diseases through the provision of immunization to women and children. Specifically, EPI has set as its target the development of services which, by 1990, can provide three doses of diphtheria, tetanus, pertussis (OPT) vaccine, three doses of polio vaccine, and one dose each of v...

OBJECTIVE Allocryptopine (ALL) is an effective alkaloid of Corydalis decumbens (Thunb.) Pers. Papaveraceae and has proved to be anti-arrhythmic. The purpose of our study is to investigate the effects of ALL on transmural repolarizing ionic ingredients of outward potassium current (I to) and slow delayed rectifier potassium current (I Ks). METHODS The monophasic action potential (MAP) techniqu...

We thoroughly study the behavioral theory of epi, a π-calculus extended with polyadic synchronization. We show that the natural contextual equivalence, barbed congruence, coincides with early bisimilarity, which is thus its co-inductive characterization. Moreover, we relate early bisimilarity with the other usual notions, ground, late and open, obtaining a lattice of equivalence relations that ...

During chemotherapy, drug resistance caused by autophagy remains a major challenge to successful treatment of cancer patients. The purpose of this study is to show that ulinastatin (UTI), a trypsin inhibitor, could reduce the resistance of liver cancer cells to chemotherapeutic agent epirubicin (EPI). We achieved this conclusion by analyzing the effect of EPI alone or UTI plus EPI on SMMC-7721 ...

This report shows that the antimicrobial peptide (AMP) Epinecidin-1 (Epi-1) efficiently heals MRSA-infected heat burn injuries and provides protection from infection in a pig model. The presence of an optimal level of Epi-1 induces cell proliferation by promoting cell cycle progression through an increase in S-phase cells. Epi-1 also induces proliferation to cover the wounded region in an in vi...

Catecholamines stimulate interleukin-6 (IL-6) secretion in skeletal muscles. However, whether other cytokines are secreted is currently unknown. Skeletal muscle ex vivo preparations commonly used to study cytokine secretion have dealt with limitations including auto-oxidation of catecholamines. The use of metal chelators could be an alternative to avoid auto-oxidation and allow catecholamines t...

Environmental Performance Index (EPI) is used to rank the performance in environment protection for most of the countries in the world. EPI is a score which gives a gauge at a national government scale using the method of proximity-to-target value. The current method fails to consider incomplete and vague environment data in its computations. This paper proposes a new score of EPI using a decis...

Energy per Instruction (EPI) is a measure of the amount of energy expended by a microprocessor for each instruction that the microprocessor executes. In this paper, we present an overview of EPI, explain the factors that affect a microprocessor’s EPI, and derive a historical comparison of the trends in EPI over multiple generations of Intel microprocessors. We show that the recent Intel® Pentiu...

PURPOSE To compare the penetration of riboflavin using a microscope-integrated real time spectral domain optical coherence tomography (ZEISS OPMI LUMERA 700 and ZEISS RESCAN 700) in keratoconus patients undergoing accelerated collagen crosslinking (ACXL) between epithelium on (epi-on) and epithelium off (epi-off). METHODS Intraoperative images were obtained during each of the procedures. Seve...