Diabetic foot ulcer (DFU) patients have a greater than twofold increase in mortality compared with nonulcerated diabetic patients. We investigated (a) cause of death in DFU patients, (b) age at death, and (c) relationship between cause of death and ulcer type. This was an eleven-year retrospective study on DFU patients who attended King's College Hospital Foot Clinic and subsequently died. A co...

BACKGROUND Offloading is key to preventing or healing plantar neuropathic foot ulcers in diabetes. Total contact casts or walkers rendered irremovable are recommended in guidelines as first-line options for offloading, however the use of such devices has been found to be low. This study aimed to investigate offloading practices for diabetes-related plantar neuropathic ulcers. METHODS An onlin...

BACKGROUND For patients with neuropathy, vasculopathy, and impairment of wound healing, treatment of a diabetic foot ulcer poses many challenges. A large number of dermal analogues have been invented in an effort to overcome these challenges. Matriderm, a dermal analogue, is made from bovine collagen and elastin. This study was conducted in order to evaluate the effectiveness of Matriderm for t...

In 2007 the IWDGF produced a consensus document on peripheral arterial disease (PAD) in diabetes. In recent years new techniques and technologies have been introduced in treating PAD, which might be relevant for the patient with diabetes and a poorly healing ischemic foot ulcer. The editorial board of International Working Group on the Diabetic Foot (IWDGF) therefore established in 2009 a multi...

BACKGROUND Foot ulceration is one of the most common complications associated with diabetes that needs to be managed. In Iran, prevalence of diabetes foot ulcer is 3%. According to studies, evidence-based nursing (EBN) is an effective alternative to facilitate clinical decision making in patient care and may lead to quality improvement in nursing practice. The aims of this study are to assess t...

Introduction : Many clients living with chronic leg and foot ulcers experience diminished quality of life, pain, psychosocial maladjustment, limited work capacity, and physical disabilities. Bibliotherapy helps the individual to cope up with illness. Objectives : Assess the pretest level of psychological distress, quality of life and depression in both Interventional and control group. Evaluate...

OBJECTIVE To determine the efficacy and safety of short-contact administration of topical tretinoin on foot ulcers in patients with diabetes. DESIGN Randomized, double-blind, placebo-controlled trial. SETTING Outpatient clinic at a Veterans Affairs medical center. PATIENTS Twenty-four volunteers with diabetic foot ulcers but without evidence of peripheral arterial disease or infection. ...

BACKGROUND Although debridement plays a significant role in the healing of diabetic foot ulcers, it may delay the healing process by damaging the granulation tissue. In this study, the efficacy of low-frequency ultrasound (LFU) in chronic wound healing in diabetic foot ulcers in patients with osteomyelitis was evaluated. METHODS This randomized clinical trial was conducted on 40 patients with...

(1) An acute phagedenic ulcer, circular in outline with sharp punched out edges usually commencing on the site of some trivial abrasion not necessarily of recent origin. The rapid increase in area and depth of the ulcer was appalling. Within 24 or 48 hours a trivial abrasion might become an ulcer as big as a rupee and with deep fascia exposed in its base. Considerable swelling of surrounding ti...