BACKGROUND Inhibition of tumour necrosis factor (TNF) is an effective way of reducing synovitis and preventing joint damage in rheumatoid arthritis (RA), yet very little is known about its specific effect on foot pain and disability. The aim of this study was to evaluate whether anti-TNF therapy alters the presence of forefoot pathology and/or reduces foot pain and disability. METHODS Consecu...

A length-dependent neuropathy with pain in the feet is a common complication of diabetes (painful diabetic neuropathy). It was hypothesized that pain may arise from sensitized-hyperactive cutaneous nociceptors, and that this abnormal signaling may be reduced by topical administration of the α(2)-adrenergic agonist, clonidine, to the painful area. This was a randomized, double-blind, placebo-con...

INTRODUCTION AND OBJECTIVE Acute injury transiently lowers local mechanical pain thresholds at a limb. To elucidate the impact of painless (diabetic) neuropathy on this post-traumatic hyperalgesia, pressure pain perception thresholds after a skeletal foot trauma were studied in consecutive persons without and with neuropathy (i.e. history of foot ulcer or Charcot arthropathy). DESIGN AND METH...

Background: Bladder carcinoma with distal bone metastasis is rare. Treatment should be multidisciplinary, including pain relief, treatment of threatening (or) pathological fractures, and oncologic therapy for bladder cancer. Case report: A 52-year-old male patient with bladder cancer reported having pain in the right foot and ankle. Xray and CT revealed multiple bone metastases of bladder cance...

BACKGROUND Plantar fasciitis is a common condition routinely managed by podiatrists in the community and is widely treated conservatively. Two commonly used treatments for plantar fasciitis are customized functional foot orthoses and corticosteroid injections. While common to clinical practice, the evidence base underpinning these treatment strategies is unknown. Therefore, the aim of this syst...

BACKGROUND Neuropathic pain is a relatively common outcome of Lyme disease. Pain management options for these patients have been limited to pharmaceutical treatments. OBJECTIVE We present a case of chronic pain following Lyme disease treated successfully using spinal cord stimulation (SCS). STUDY DESIGN Case report. SETTING Pain management clinic. METHODS A 62-year-old patient presented...

Introduction. The Manchester Foot Pain and Disability Index (MFPDI) is a 19-item questionnaire for the assessment of disability caused by foot pain. The aim was to develop a Danish language version of the MFPDI (MFPDI-DK) and evaluate its reproducibility and construct validity. Methods. A Danish version was created, following a forward-backward translation procedure. A sample of 84 adult patien...

Background Gout is on the increase worldwide and is the most common form of inflammatory arthritis affecting men. Gout is of particular significance to New Zealand, affecting approximately 15% of Maori and Pacific men in South Auckland, thus it has been dubbed the ‘gout capital of the world’. Gout most frequently affects the foot, with initial attack affecting in the first metatarsophalangeal j...