C−F Insertion reactions represent an attractive approach to prepare valuable fluorinated compounds. The high strength of bonds and the low reactivity fluoride released upon bond cleavage, however, mean that examples such processes are extremely scarce in literature. Here we report a reaction system overcomes these challenges using hydrogen donors both activate allow for downstream with fluoride...

To discover novel scaffolds as leads against dementia, a series of δ-aryl-1,3-dienesulfonyl fluorides with α-halo, α-aryl and α-alkynyl were assayed for ChE inhibitory activity, in which compound A...