The applicability of the activation of an NaI scintillator for neutron monitoring at a clinical linac was investigated experimentally. Thermal neutron fluence rates are derived by measurement of the I-128 activity generated in an NaI scintillator irradiated by neutrons; β-rays from I-128 are detected efficiently by the NaI scintillator. In order to verify the validity of this method for neutron...

Intensity-modulated radiation therapy (IMRT) is a state-of-the-art technique for administering radiation to cancer patients. The goal of a treatment is to deliver a prescribed amount of radiation to the tumor, while limiting the amount absorbed by the surrounding healthy and critical organs. Planning an IMRT treatment requires determining fluence maps, each consisting of hundreds or more beamle...

The relation between the cosmological evolution of the jet-disk symbiosis model for GRBs and the cosmic rays energy distribution is presented. We used two different Star Formation Rates (SFR) as a function of redshift and a Luminosity Function (LF) distribution to obtain the distribution in fluence of GRBs in our model and compare it with the data. We show a good agreement between the fluence d...

The environmental neutron spectrum has been measured at Zacatecas City in Mexico. Neutron spectrum was unfolded from count rates obtained with a multisphere neutron spectrometer with a LiI(Eu) scintillator. With the spectrum information the ambient dose equivalent and the isotropic effective dose were calculated. A model based upon the geomagnetic latitude and the altitude above sea level, that...

At high fluence rates in animal models, photodynamic therapy (PDT) can photochemically deplete ambient tumor oxygen through the generation of singlet oxygen, causing acute hypoxia and limiting treatment effectiveness. We report that standard clinical treatment conditions (1 mg/kg Photofrin, light at 630 nm and 150 mW/cm2), which are highly effective for treating human basal cell carcinomas, sig...

The main approach to smooth Pareto surface navigation for radiation therapy multi-criteria treatment planning involves taking real-time averages of pre-computed treatment plans. In fluencebased treatment planning, fluence maps themselves can be averaged, which leads to the dose distributions being averaged due to the linear relationship between fluence and dose. This works for fluence-based pho...

Helium ion microscopy (HIM) was used to investigate the interaction of a focused He(+) ion beam with energies of several tens of kiloelectronvolts with metals. HIM is usually applied for the visualization of materials with extreme surface sensitivity and resolution. However, the use of high ion fluences can lead to significant sample modifications. We have characterized the changes caused by a ...

The authors compare the effects of focused and broad MeV ion beam irradiation on the surface roughness of silicon wafers after subsequent electrochemical anodization. With a focused beam, the roughness increases rapidly for low fluences and then slowly decreases for higher fluences, in contrast to broad beam irradiation where the roughness slowly increases with fluence. This effect is important...

Photoacoustic tomography (PAT) is a hybrid imaging technique that has broad preclinical and clinical applications. Based on the photoacoustic effect, PAT directly measures specific optical absorption, which is the product of the tissue-intrinsic optical absorption coefficient and the local optical fluence. Therefore, quantitative PAT, such as absolute oxygen saturation (sO₂) quantification, req...