For the full versions of these articles see bmj.com Egg allergy affects about 2.6% of preschool children by 3 years of age, and influenza immunisation using egg based vaccines has been classified as a " relative contra indication " (prescribe with extra caution) in this patient group. 1 Until now the numbers of children with egg allergy requiring immunisation has been low, but this may change w...

In the present work, preferential binding mode of Fluorometholone (FLU) drug into nanopores two cyclodexterins, b-cyclodextrin (b-CD) and sulfobutylether-b-cyclodextrin (SEB-b-CD), are theoretically investigated using density functional theory (DFT), Docking, molecular dynamics (MD) simulation MM-PBSA free energy calculations. The computational results reveal that hydrogen bonds (HBs) van der W...

Abstract Development of universal influenza (flu) vaccines requires better knowledge lung-resident immune responses. That includes flu-specific CD4 T cells, which establish long-term lung residency and induce a diversified local protective response to subsequent infection. Tissue-resident helper (Trh) cells are subset that share phenotypic functional features with follicular (Tfh). Trh serve am...