Abstract: properties of AA6082 aluminum alloy. Considering that aging phenomenon affects the distribution of alloying elementin matrix, and the fact that different distribution of alloying elements has different impediments to dislocationmovement, a material model based on microstructure, has been developed in this research. A relative volume fractionor mean radius of precipitations is introduc...

Four muhiparous ovariectomized ewes, fitted with electromagnetic blood flow transducers around one mid-uterine artery, were utilized in two latin square design C.xperiments to evaluate interrelationships of thermal stress and epinephrine on an increase in uterine blood flow (UBF) induced by estradiol. Estradiol (20 /ag) was injected into the femoral vein and the subsequent induced increase in U...

The effect of shear stress at the endothelium in the attenuation of the noradrenaline-induced constriction of the femoral vascular bed perfused at a constant blood flow was investigated in 16 anesthetized cats. It is known that the adrenergic vasoconstriction of the femoral vascular bed is considerably greater at a constant pressure perfusion than at a constant blood flow. This difference may d...

The effects of viscosity on the irrotational motions of spherical cap bubble, Taylor bubbles in round tubes, Rayleigh-Taylor and Kelvin-Helmholtz instability described in previous chapters were obtained by evaluating the viscous normal stress on potential flow. In gas-liquid flows, the viscous normal stress does not vanish and it can be evaluated on the potential. It can be said that in the cas...

Shear stress activates cellular signaling involved in cellular proliferation, differentiation, and migration. However, the mechanisms of mesenchymal stem cell (MSC) differentiation under interstitial flow are not fully understood. Here, we show the increased osteogenic differentiation of MSCs under exposure to constant, extremely low shear stress created by osmotic pressure-induced flow in a mi...

Chronic stress is associated with increased risk of cardiovascular diseases. Aging is also associated with vascular dysfunction. We hypothesize that chronic stress accelerates collateral dysfunction in old mice. Mice were subjected to either chronic social defeat (CSD) or chronic cold stress (CCS). The CSD mice were housed in a box inside an aggressor's cage and exposed to the aggressor. The CC...

BACKGROUND Magnetic resonance imaging (MRI) is a versatile technique for examination of the cardiovascular system but only recently has assessment of myocardial ischaemia in coronary artery disease (CAD) become possible, for example by demonstrating abnormalities of regional ventricular contraction during stress. Global ventricular function during stress was assessed by MRI of aortic flow, whic...

Synovial joints are loaded by weight bearing, stretching, and fluid-driven shear. To simulate in vitro fluid-driven shear, we developed an "oscillating Couette flow mechanical shear loader". Oscillating Couette flow mimics relative motion of articular surfaces; hence, characterizing flow-induced shear by the loader enhances understanding of mechanotransduction in the joint tissue. Here, the ana...

Skeletal muscle arterioles dilate in response to increases in flow velocity/wall shear stress (WSS). The effect of flow/WSS on the diameter of skeletal muscle venules and the possible endothelial mediation of the response, however, have not yet been characterized. Thus changes in diameter of pressurized (10 mmHg) and norepinephrine-preconstricted venules (179 ± 8 μm in diameter) to increases in...

A mathematical analysis has been carried out for the axial flow of a Bingham plastic fluid, in the Concentric Cylinder Viscometer which consists of a cylindrical sample holder (the cup) and a cylindrical spindle (the bob) coaxial with the cup. The fluid to be tested flows through the annular gap of the cup and the bob system, sheared by the rotation of the inner cylinder, while the outer cy...