This work aimed to prepare a nanoemulsion preparation containing budesonide and assess its aerodynamic behavior in comparison with suspension of budesonide. In-vitro aerodynamic performance of the corresponding micellar solution (ie. nanoemulsion preparation without oil) was investigated too. Nanoemulsions of almond oil containing budesonide, as a hydrophobic model drug molecule, were prepared ...

BACKGROUND The sum of eicosapentaenoic acid (EPA, 20:5 omega3) and docosahexaenoic acid (DHA, 22:6 omega3) in erythrocyte membranes, termed the omega-3 index, can indicate suboptimal intake of omega-3 fatty acids, a risk factor for cardiovascular disease (CVD). To study the effects of fatty acid supplementation, we investigated the rate of incorporation and clearance of these fatty acids in ery...

This paper reviews the effects of the addition of flaxseed gum on the physicochemical properties of whey protein-stabilized, oil-in-water emulsions at neutral and acidic pH as investigated by light scattering and rheology under dilute and concentrated conditions. At pH 7.0, measurements performed in the dilute system showed no changes in charge or size of the droplets however, in the concentrat...

the topical delivery of non-steroidal anti-inflammatory drugs (nsaids) such as ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. however, it is dif...

Flaxseed oil is a high nutrition oil, rich in ω-3 fatty acid, tocopherols and phenolic compounds. However, it prone to oxidation due its unsaturation which needs pretreatments be easily introduce the market. In this study, flaxseed was converted powder form by mixing with microcrystalline cellulose (MC) thyme produce powder. For purpose, 3 different levels of (5%, 10% 15% oil) were mixed follow...