A 29-year-old Caucasian man presented to an outside clinic with an erythematous, exophytic, eroded tumor on his right heel; a biopsy showed acral lentiginous malignant melanoma, with a Breslow depth of 2.01 mm, ulceration, and one dermal mitosis per square millimeter. He underwent wide local excision with 3 cm margins as well as right popliteal and right inguinal sentinel lymph node biopsies, w...

The right to health is a human right. Every person has the right to enjoy the highest attainable standard of health. However, for many people, enjoyment of this right is far from reality—for example, many do not have access to effective and affordable medicine and treatments or to safe drinking water, adequate food, and basic sanitation. Some progress has been made, such as in women’s and child...

Introduction: Pain as a complex process in the CNS has been extensively studied by many researchers. It has been found that pain is controlled by certain pathways in the CNS, one of most important of which is the descending noradrenergic system. The pathway begins with Locus Coeruleus (LC) nucleus and ends in the spinal cord. In this study, formalin test was used as a chemical and tonic pain...