نتایج جستجو برای: fih at this paper
تعداد نتایج: 7715070 فیلتر نتایج به سال:
Two transient receptor potential (TRP) channels-TRPA1 and TRPV3-are post-translationally hydroxylated, resulting in oxygen-dependent regulation of channel activity. The enzymes responsible are the HIF prolyl hydroxylases (PHDs) and the asparaginyl hydroxylase factor inhibiting HIF (FIH). The PHDs and FIH are well characterized for their hydroxylation of the hypoxic inducible transcription facto...
ihpmagazine.com { April/May 2011 IHP | 8
Received Jul. 6 th , 2013 Accepted Jul. 21 st , 2013 Hypoxia inducible factor (HIF) is the main protein in hypoxia pathway. The response of HIF to changes of oxygen pressure is regulated by 2 oxygen sensors, prolyl hydroxylase (PHD) and factor inhibiting HIF (FIH). Studies have shown that biochemical reactions at molecular level actually exhibit stochastic and random behaviors. Modeling biochem...
BACKGROUND First-in-human (FIH) trials of low-molecular-weight anticancer agents conventionally derive a safe start dose (SD) from one-tenth the severely toxic dose in 10% of rodents or one-sixth the highest nonseverely toxic dose (HNSTD) in nonrodent species. No consensus has been reached on whether this paradigm can be safely applied to biotechnology-derived products (BDPs). MATERIALS AND M...
this study gives a rough notional method to find their textual placing and valuating in the text, narrows the board of vision to mystic items and finally lists the strategies used by the translators of mathnawi to present solutions for preserving the additional values. at last, as the sum-up, strategies in comparison would be presented. it should be noted that by extending the translations from...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید