نتایج جستجو برای: fibromodulin
تعداد نتایج: 210 فیلتر نتایج به سال:
INTRODUCTION: The bone regeneration process is characterized by hematoma formation, inflammation, angiogenesis, chondrogenesis, osteogenesis and bone remodeling. Mesenchymal stem cells (MSCs) are crucial during the early phase of bone healing, possibly acting via migration, proliferation and differentiation into functional cells of the chondrogenic or osteogenic lineage. In addition to biologic...
The expression of components present in the cartilaginous extracellular matrix is related to development, gender, and genotype, as well as to the biomechanical properties of each type of cartilage. In the present study, we analyzed small proteoglycans and glycosaminoglycans present in different cartilages of the chicken wing after extraction with guanidine hydrochloride or papain. Quantitative ...
Osteoarthritis (OA) is the most common form of arthritis and has multiple risk factors including joint injury. The purpose of this study was to characterize the histologic development of OA in a mouse model where OA is induced by destabilization of the medial meniscus (DMM model) and to identify genes regulated during different stages of the disease, using RNA isolated from the joint "organ" an...
RATIONALE Inflammatory mechanisms have been suggested to play a role in the development of heart failure (HF), but a role for chemokines is largely unknown. Based on their role in inflammation and matrix remodeling in other tissues, we hypothesized that CXCL13 and CXCR5 could be involved in cardiac remodeling during HF. OBJECTIVE We sought to analyze the role of the chemokine CXCL13 and its r...
Local biochemical and morphological differences in human Achilles tendinopathy: a case control study
BACKGROUND The incidence of Achilles tendinopathy is high and underlying etiology as well as biochemical and morphological pathology associated with the disease is largely unknown. The aim of the present study was to describe biochemical and morphological differences in chronic Achilles tendinopathy. The expressions of growth factors, inflammatory mediators and tendon morphology were determined...
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