نتایج جستجو برای: fibrin matrix
تعداد نتایج: 376150 فیلتر نتایج به سال:
Background and Aims: Tissue engineering is a relatively novel field that has been intensely developing during recent years and has shown to be excessively promising when used for cartilage regeneration. Scaffolds represent important components for tissue engineering. Materials and Methods: The Poly Lactic-Co-Glycolic Acid (PLGA) impregnated with fibrin and hyaluronic acid (HA) produce hybrid s...
Objective(s):The aim of this study was to compare the chondrogenic induction potential of Piascledine and TGF-β1 on adipose-derived stem cells (ADSCs) in fibrin and fibrin-alginate scaffolds. Materials and Methods: Human subcutaneous adipose tissues were harvested from three patients who were scheduled to undergo liposuction. Isolated ADSCs were proliferated in a culture medium. Then, the cell...
Platelet-rich fibrin, developed in France by Choukroun et al., is a second generation platelet concentrate widely used to accelerate soft and hard tissue healing. It is a strictly autologous fibrin matrix containing a large quantity of platelet and leukocyte cytokines. It has also been shown to stimulate the growth of osteoblasts and periodontal ligament cells, both of which are significant for...
tranexamic acid is generally used in the treatment of disorders that predispose one to bleeding. it is a synthetic lysine analog that has strong antifibrinolytic activity. plasminogen binds to fibrin to form plasmin, which in turn degrades fibrin into fibrin degradation products. tranexamic acid blocks the lysine binding site on plasminogen and prevents interaction with fibrin. tranexamic acid ...
Abstract AIMS To succeed in clinical trials for glioblastoma we need vitro models capable of more faithfully replicating dis- ease biology and accurately predicting patient drug responses. this end, new bioprinting technologies have the potential to biofabricate clinically relevant biomimetic tissues which can accelerate discovery additionally serve as a platform personalized medicine. METHOD W...
Mesenchymal stem cells are showing increasing promise in applications such as tissue engineering and cell therapy. MSC are low in number in bone marrow, and therefore in vitro expansion is often necessary. In vivo, stem cells often reside within a niche acting to protect the cells. These niches are composed of niche cells, stem cells, and extracellular matrix. When blood vessels are damaged, a ...
Acute inflammatory and chronic interstitial lung diseases are characterized by excessive and persistent fibrin deposition in the lung. Intraalveolar fibrin accumulation, observed under these conditions, arises from a leakage of plasma proteins (including fibrinogen) into the alveolar space in combination with a disbalance of alveolar haemostasis. Tissue factor in association with factor VIIa an...
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