Growth factor-induced stress fiber formation involves signal transduction through Rac and Rho proteins and production of leukotrienes from arachidonic acid metabolism. In exploring the relationship between these pathways, we found that Rac is essential for EGF-induced arachidonic acid production and subsequent generation of leukotrienes and that Rac V12, a constitutively activated mutant of Rac...

In this paper, a 50 Km remote and switchable fiber optic sensing system based on an erbium doped fiber ring laser is proposed. The system allows the integration of different interrogation methods based on the detection of wavelength or amplitude variations of the laser. This integration is carried out by sequentially activating different ring cavities by using an optical switch. With this schem...

Through five experiments, we demonstrate and characterize the basic functionality of imaging fiber bundles for optoelectronic chip-level interconnections. We demonstrate the transmission of spot arrays with spot sizes and a spot pitch roughly equal to 2 and 4 times the core pitch, respectively. We show that optoelectronic integrated circuits, including sources and detectors, can be butt coupled...

In the five experiments described in this paper we demonstrate and characterize the basic functionality of imaging fiber bundles for optoelectronic chip level interconnections. We demonstrate the transmission of spot arrays with spot sizes and spot pitch roughly equal to two and four times the core pitch respectively. We show that optoelectronic integrated circuits, including sources and detect...

This paper presents an experimental and numerical study of unidirectional carbon fiber composites with a silicone matrix, loaded transversally to the fibers. The experiments show nonlinear behavior with significant strain softening under cyclic loading. The numerical study uses a plane-strain finite element continuum model of the composite material in which the fiber distribution is based on ex...

A fiber-like lattice with resistively coupled electronic elements mimicking a 1-D discrete reactiondiffusion system is considered. The chosen unit or element in the fiber is the paradigmatic Chua’s circuit, capable of exhibiting bistable, excitable, oscillatory or chaotic behavior. Then the dynamics of a structure of two such interacting parallel active fibers is studied. Suitable conditions fo...

We present a configuration for surface plasmon resonance sensors based on uniform-waist tapered optical fibers and reflective elements. Once the fiber is tapered fulfilling the adiabatic criterion, a multilayer including a metallic medium is asymmetrically deposited on the uniform waist of the fiber. This feature provides the resonant excitation of multiple surface plasma waves. In addition, a ...

A novel, two-scale computational model has been developed to predict the progressive damage and failure responses of fiber-reinforced composite laminates using the material properties at the constituent (fiber and matrix) level. These properties were measured from coupon level tests on a unidirectional lamina of the same material system. In the proposed computational scheme, the macroscale fini...

DNA methylation is essential for plant and animal development. In plants, methylation occurs at CG, CHG, and CHH (H = A, C or T) sites via distinct pathways. Cotton is an allotetraploid consisting of two progenitor genomes. Each cotton fiber is a rapidly-elongating cell derived from the ovule epidermis, but the molecular basis for this developmental transition is unknown. Here we analyzed methy...

Functional interactions between different brain regions require connecting fiber tracts, the structural basis of the human connectome. To assemble a comprehensive structural understanding of neural network elements from the microscopic to the macroscopic dimensions, a multimodal and multiscale approach has to be envisaged. However, the integration of results from complementary neuroimaging tech...