Circulating nucleic acids are present in small amounts in the plasma of healthy individuals. However the discovery of circulating nucleic acids has long been explored for the noninvasive diagnosis of a variety of clinical conditions. The first studies concerning the detection of circulating DNA were investigated for finding various forms of cancer. Metastasis and recurrence in certain tumour ty...

Circulating nucleic acids are present in small amounts in the plasma of healthy individuals. However the discovery of circulating nucleic acids has long been explored for the noninvasive diagnosis of a variety of clinical conditions. The first studies concerning the detection of circulating DNA were investigated for finding various forms of cancer. Metastasis and recurrence in certain tumour ty...

INTRODUCTION Studies have shown that fetal progenitor cells persist in maternal blood or bone marrow for more than 30 years after delivery. Increased trafficking of fetal cells occurs during pregnancy complications, such as hypertension, preeclampsia, miscarriage and intra-uterine growth restriction (IUGR). Women with these pregnancy complications are significantly more often HLA-class II compa...

Objectives: Facilitate risk assessment of vital complications in fetuses of pregnancies affected by acute parvovirus B19 infection. Design: Study of the natural course of maternal parvovirus B19 infection in four cases, from early pregnancy on. Setting: University medical center in the Netherlands. Population: Pregnant mothers attending obstetric services. Methods: Serial measurements of the ma...

Objectives: To find out the maternal and fetal complications of twin gestation and to assess the effect of these complications on perinatal outcome. Material and Methods: This Descriptive study was carried out in Gynae B Unit of Khyber Teaching Hospital, Peshawar from January 2010 to December 2010. A total of 50 patients with twin pregnancy who had completed 28 weeks of twin gestation both book...

Preconception and prenatal monitoring evaluate the condition of mother's underlying disease possible complications during pregnancy. Before conception, patients with diabetes should be informed that suboptimal glycoregulation is associated reduced fertility pregnancy losses. The task perinatologist in pregnancies affected by mellitus to prevent disease, such as hypoglycemic crises. Another impo...

OBJECTIVE Maternal alloimmunization to fetal red-blood-cell antigens is a major cause of fetal anemia, which can lead to hydrops and perinatal death if untreated. The cornerstone of management during pregnancy is intrauterine intravascular blood transfusion (IUT). Although this procedure is considered relatively safe, complications continue to occur. The aim of this study was to evaluate rates ...

Thyroid pathology worsens during pregnancy. Hypothyroidism can be pre-existent or may begin during pregnancy period. Most of the patients who presented hypothyroidism during pregnancy have a history of thyroid disease for which they have undergone treatment (medical, surgical or radioisotopes). Hypothyroidism is difficult to be diagnosed during pregnancy as the signs can belong to pregnancy its...