In recent years, there has been much importance placed on finding novel therapeutic agents from F. asafoetida plant and it’s common name is Asafoetida. It is commonly used as a traditional medicine in Iran, Afghanistan and India. It is herbaceous plant of the Umbelliferae family and its root contains oleo gum resin which has many medicinal properties. The resin is solid or semisolid with alliac...

Several complications attributed with Herpes virus related infections and the emergence of drug resistant viruses prompt scientists to search for new drugs. Several terpenoids and coumarins have shown anti HSV effects while no sesquiterpene coumarin have been previously tested for HSV treatment. Three sesquiterpene coumarins [badrakemin acetate (1), kellerin (2) and samarcandin diasteromer (3) ...

This study investigated the anticonvulsant activity and possible mechanism of action of an aqueous solution of Dorema ammoniacum gum (DAG) which has been used traditionally in the treatment of convulsions. In this study, the anticonvulsant activity of DAG was examined using the pentylentetrazole (PTZ) model in mice. Thirty male albino mice were divided randomly and equally to 5 groups, and pret...

In this experiment, the chemical composition of the essential oils obtained from Ferula assa-foetida oleo-gum resin collected from two different sites of Yazd province (Tabas and Yazd) in the center of Iran, were identified. The gas chromatography mass-spectroscopy (GC/MS) data showed that the qualitative composition of the components appeare...

background and objectives: pseudomonas aeruginosa is a gram-negative, aerobic bacterium found in water and soil. it is a normal flora in skin and gastrointestinal tract of human beings. p. aeruginosa as an opportunistic pathogen involved in nosocomial infections having multiple pathogenic factors and shows high rate of resistance to different antibiotics. the aim of this study was to identify t...

introduction: oxidative degradation of lipids is a major factor limiting the shelf life of foods. the free radical reaction of lipid peroxidation is generally responsible for the deterioration of fatty foods. in general, use of synthetic antioxidants during the manufacturing process are applied to prevent fat oxidative and rancidity while their carcinogenic effects have been approved. since the...