Galbanic acid, a sesquiterpene coumarin from Ferula szowitsiana roots, was investigated for its potentiating effect on the antimicrobial activity of antibiotics as well as ethidium bromide, in 6 multidrug resistance (MDR) clinical isolates of Staphylococcus aureus. Galbanic acid had inhibitory effect on none of the isolated bacteria tested (up to 800 μg /ml). The MIC range of ciprofloxacin, tet...

Marino, P., Schicchi, R., Barone, E., Raimondo F. M. & Domina G.: First results on the phenotypic analysis of wild and cultivated species of Pyrus in Sicily. — Fl. Medit. 23: 237-243. 2013. — ISSN: 1120-4052 printed, 2240-4538 online. Phenotypic analysis of Pyrus in Sicily using a set of 19 characters on 71 accessions belonging to 7 species is here reported. Results show a high level of morphol...

Medical plants are adapted to different kinds of dormancy to survive in the worst situations. Regarding to ecological viewpoint, this kind of adaptation is very important in respect to restriction of genetic draft and decrease of genetic resource of medicinal plants. This leads to plant survival even after prolonged drought. Since some of them are endangered species and in the other hand increa...

In Iranian traditional medicine, there are some report regarding the anticonvulsant effect of Ferula gummosa Boiss. In this study, anticonvulsant activity, neurological deficits and lethality of the root acetone extract of this plant were evaluated in mice. The extract exhibited dose-dependent prevention of tonic seizures induced by pentylenetetrazole (ED50 = 154.4 mg/kg). However, the extract ...