نتایج جستجو برای: ferritin

تعداد نتایج: 10628  

2015
Jae-Woo Kim Do Hoon Kim Yong Kyun Roh Sang Yhun Ju Hyo-Yun Nam Ga-Eun Nam Dong-Won Kim Seung-Hyun Lee Chung-Woo Lee Kyungdo Han Yong-Gyu Park

The purpose of this study was to examine the relationship between serum ferritin levels and metabolically obese normal weight (MONW) and to determine the appropriate cut-off value of serum ferritin for the prediction of clinical metabolic status in nonobese Korean adults. Data from 9411 participants in the fourth (2008) and fifth (2010) annual Korea National Health and Nutrition Examination Sur...

Journal: :American journal of nephrology 2010
Takeshi Nakanishi Takahiro Kuragano Masayoshi Nanami Yoshinaga Otaki Hiroshi Nonoguchi Yukiko Hasuike

The clinical significance of serum ferritin in monitoring the iron status of patients on maintenance hemodialysis (MHD) has become suspected. In this review, we reassess the interpretation of high serum ferritin values in such patients, with the goal of treating their anemia in a safe way. From the observations that (1) H-ferritin gene transcription is predominantly active in inflammatory condi...

Journal: :The Biochemical journal 2010
Marc Mikhael Alex D Sheftel Prem Ponka

Iron is essential for all life, yet can be dangerous under certain conditions. Iron storage by the 24-subunit protein ferritin renders excess amounts of the metal non-reactive and, consequentially, ferritin is crucial for life. Although the mechanism detailing the storage of iron in ferritin has been well characterized, little is known about the fate of ferritin-stored iron and whether it can b...

Journal: :Clinical science 1995
N H Chow C J Chang P E Cheng T S Tzai C M Huang J S Lin

1. The serum ferritin level provides a valuable index of the body iron store. An increase in serum ferritin has often been observed in patients with neoplastic disease and correlates well with the stage of cancer. A few studies have suggested the potential of urinary ferritin as a marker for transitional cell carcinoma. The rationale of the measurement, however, has not been investigated in det...

Journal: :Blood 1991
S Fargion A L Fracanzani B Brando P Arosio S Levi G Fiorelli

Interactions between human recombinant H- and L-ferritins and human lymphocytes were studied in vitro by direct binding assays and by flow cytometry. L-ferritin did not cause detectable specific binding, whereas H-ferritin showed a specific and saturable binding that increased markedly in phytohemagglutinin (PHA)-stimulated cells. This ferritin bound up to 30% of CD4+ and CD8+ T-lymphocytes and...

Journal: :The Journal of Experimental Medicine 2005
Thomas T. Chen Li Li Dong-Hui Chung Christopher D.C. Allen Suzy V. Torti Frank M. Torti Jason G. Cyster Chih-Ying Chen Frances M. Brodsky Eréne C. Niemi Mary C. Nakamura William E. Seaman Michael R. Daws

T cell immunoglobulin-domain and mucin-domain (TIM) proteins constitute a receptor family that was identified first on kidney and liver cells; recently it was also shown to be expressed on T cells. TIM-1 and -3 receptors denote different subsets of T cells and have distinct regulatory effects on T cell function. Ferritin is a spherical protein complex that is formed by 24 subunits of H- and L-f...

2005
YASUKAZTJ TANAKA GEORGE BRECHER

Effect of SI level and saturation of TIBC on the induction of ferritin in erythroid cells was investigated in rats, guinea pigs, and rabbits. Evidence presented indicates that species difference and serum iron level are important factors in induction of micropinocytotic ferritin in developing erythroid cells: (1) Micropinocytotic ferritin was occasionally seen in erythroblasts of control guinea...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2000
K Y Yeh M Yeh J Glass

To cope with increasing dietary iron exposure, the intestinal epithelium of weaning rats must control intracellular labile iron pools. Intestinal expression of heavy (H) and light (L) ferritin subunits during early weaning and after cortisone administration and/or iron feeding was investigated. Changes in H and L ferritin gene expression were determined by nuclear runoff transcriptional assay, ...

Journal: :Journal of Insect Science 2002
Boris C. Dunkov Teodora Georgieva Toyoshi Yoshiga Martin Hall John H. Law

Secreted ferritin in the mosquito, Aedes aegypti, has several subunits that are the products of at least two genes, one encoding a homologue of the vertebrate heavy chain (HCH) and the other the light chain homologue (LCH). Here we report the developmental and organ specific pattern of expression of the ferritin HCH messages and of both subunit types in control sugar-fed mosquitoes, in those ex...

2012
Jee-Yon Lee Jae-Min Park Jung-Ah Hong Duk-Chul Lee Jee-Aee Im Ji-Won Lee

BACKGROUND Ferritin is known to be associated with insulin resistance (IR) and oxidative stress; however, recent studies have shown that there is an association between ferritin and anti-oxidative status. To date, the biphasic response of ferritin to oxidative stress has not been fully evaluated. Thus, we investigated the association between ferritin and IR and anti-oxidative status in obese an...

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