Ginseng, a perennial plant belonging to the genus Panax of the Araliaceae family, is well known for its medicinal properties that help alleviate pathological symptoms, promote health, and prevent potential diseases. Among the active ingredients of ginseng are saponins, most of which are glycosides of triterpenoid aglycones. So far, numerous saponins have been reported as components of Panax gin...

Background and objectives: Sedentary life style and high-fat diet are one of the key causes of coronary artery disease. The aim of this study was to evaluate effects of periodic exercise and consumption of fenugreek seed extract on the expression of oxidized low-density lipoprotein (oxLDL) and reactive oxygen species (ROS) genes in patients with coronary artery occlusion. Methods: The present ...

Globally a large number of people are affected by acute and chronic diseases resulting in high morbidity mortality rate. A huge amount pharmaceutical drugs being manufactured on daily basis to combat these diseases. But due their cost deleterious effects, it becomes critically important state emphasis finding an alternative way manage long term conditions. Medicinal herbs could provide good sou...

conclusions it appears that fenugreek seed might be effective against hyperglycemia, hyperlipidemia and insulin resistance in ovariectomized rats without impact on serum apelin. furthermore, 17-β estradiol could have similar effects along with possible inhibitory effects on serum apelin. the complicated role of apelin in menopause needs to be further explored. results serum apelin, glucose, lip...

abstract in order to study the effect of different organ extracts of fenugreek (trigonella gracum (on germination of some crops and weeds, an experiment was conducted in completely randomized design with 3 replications. factors included 4 species soybean (glysin max),sesame ( sesamus indicum) , pigweed (amaranthus retroflexus) and velvetleaf (abotilon teophrasti) and the extract of different fe...

In this study, alkali dietary fiber extraction method was evaluated to obtain soluble and insoluble from Trigonella-foenum graecum L. (fenugreek) seeds. The process conditions of ensuring the highest total yield were investigated by response surface methodology. Furthermore, some physicochemical functional properties extracted fenugreek seeds such as water retention capacity, oil adsorption swe...

Triterpene saponins (saponosides) are found in a variety of higher plants and display a wide range of pharmacological activities, including expectorant, anti-inflamatory, vasoprotective, gastroprotective and antimicrobial properties. Recently, a potential anticancer activity of saponins has been suggested by their cytotoxic, cytostatic, pro-apoptotic and anti-invasive effects. At high concentra...

Saponins are widely distributed in the plant kingdom and have been shown to be active components of many medicinal herbs. In this study, a two-dimensional purification method based on reversed-phase liquid chromatography coupled with hydrophilic interaction liquid chromatography was successfully applied to purify saponins from leaves of Panax notoginseng. Nine saponin reference standards were u...

Sea cucumbers are prolific producers of a wide range of bioactive compounds. This study aimed to purify and characterize one class of compound, the saponins, from the viscera of the Australian sea cucumber Holothuria lessoni. The saponins were obtained by ethanolic extraction of the viscera and enriched by a liquid-liquid partition process and adsorption column chromatography. A high performanc...

In the present study the adaptogenic activities of the saponin fractions of the leaves and roots of Polyscias fruticosa (L) Harms (Araliaceae) were studied in comparision wit white panax ginseng root saponins. The antibacterial activity of the polyacetylenic compound in leaves were also studied. The adaptogenic activity studies showed that polyscias fruticosa leaf and root saponins have effecti...