Bis(phosphinidene)-capped triiron carbonyl clusters, including electron rich derivatives formed by substitution with chelating diphosphines, have been prepared and examined as proton reduction catalysts. Treatment of the known cluster [Fe3(CO)9(µ3-PPh)2] (1) various diphosphines in refluxing THF (for 5, toluene) afforded new clusters [Fe3(CO)7(µ3-PPh)2(κ2-dppb)] (2), [Fe3(CO)7(µ3-PPh)2(κ2-dppv)...

Ascorbic acid (AA) has antioxidant properties. However, in the presence of Fe2+/Fe3+ ions and H2O2, it may behave as a pro-oxidant by accelerating enhancing formation hydroxyl radicals (•OH). Therefore, this study we evaluated effect AA at concentrations 1 to 200 µmol/L on •OH-induced light emission (at pH 7.4 temperature 37 °C) from 92.6 Fe2+—185.2 EGTA (ethylene glycol-bis (β-aminoethyl ether...

In this study, we prepared novel fluorescent carbon quantum dots/hydrogel nanocomposite material (CQDsHG) with good adsorption and stable fluorescence detection of Fe3+. The materials were subsequently characterized according to their morphological features, chemical composition, adsorption, optical properties. dots (CQDs) using a microwave-assisted hydrothermal method in no more than 15 min, t...

Iron is a limiting factor that controls the phytoplankton biomass of ocean and plays an important role in lipid production microalgae. Elucidating effects different iron valences on microalgae helpful for their commercial production. We investigated growth, photosynthesis, fatty acid profile model diatom Phaeodactylum tricornutum cultured with depleted Fe, Fe2+, Fe2+/Fe3+, Fe3+. Samples were ta...

Aluminum, a trivalent cation unable to undergo redox reactions, is shown to faciliate iron-initiated DOPA oxidation in the melanin pathway under acidic condition of pH 5.5, which is a favored medium for aluminum facilitation of iron-induced lipid peroxidation. In the process of oxidation of DOPA to melanin in the presence of the metal ions, Fe3+ and H2O2 oxidize DOPA to dopachrome (DC), then Al...

The oxidation of N-hydroxylated compounds may result in production of nitrogen oxides, including nitric oxide (NO). Oxidation may be independent on NO-synthase. Production of nitrites and nitrates via NO from formaldoxime and glyceryl trinitrate was studied and compared. Superoxide ion, ions Fe2+ and Fe3+, methemoglobin and methemoglobin + NADPH + methylene blue, oxyhemoglobin and oxyhemoglobin...

Cyclin D1 has become a potential target for anti-tumor therapy. Recently, a novel human anti‑cyclin D1 single‑chain variable fragment (AD5) was identified, which demonstrated specific binding activity to cyclin D1 and exhibited anti‑tumor effects. However, the detailed characteristics of AD5 remain unclear. In the present study, the structure and activity of AD5 in the presence of copper II (Cu...

Derivatives of 3,4-hydroxypyridinones have been extensively studied for in vivo Fe3+ sequestration. Deferiprone, a 1,2-dimethyl-3,4-hydroxypyridinone, is now routinely used for clinical treatment of iron overload disease. Hexadentate tris(3,4-hydroxypyridinone) ligands (THP) complex Fe3+ at very low iron concentrations, and their high affinities for oxophilic trivalent metal ions have led to th...