The events leading to the completion of cytokinesis after the formation of the midbody and intercellular bridge in D-98S cells were studied with light and electron microscopy. Pairs of daughter cells corresponding to different stages of cytokineses, as determined previously form time lapse films, were selected from embedded monolayers for serial sectioning. Separation of daughter cells is prece...

In a family with a remarkable aggregation of malignant mesothelioma the father, mother, and a son all died of the condition, whereas two other sons and a daughter were unaffected. From 1944 to 1961 the family produced a material that was used to fix screws in drilled holes and consisted of amosite, gypsum, and sand. It was produced in the basement of their villa and was described as being a dus...

We report the kindred with familial isolated hyperparathyroidism with parathyroid cancer. The proband was diagnosed as having primary hyperparathyroidism at age 43. The same disorder was also found in his daughter who had low bone mass. His son was found to have primary hyperparathyroidism by family screening. The pathological diagnosis of the resected parathyroid in both father and daughter wa...

INTRODUCTION Peutz-Jeghers syndrome (PJS) is a rare disorder characterized by mucocutaneous perioral pigmentation, gastrointestinal hamartomatous polyposis, and an increased risk of malignancy. Families with PJS may show a variable spectrum of manifestations in spite of their consecutive generations. A probable explanation is novel mutations in contributing genes. CASE PRESENTATION This repor...

Fisher’s name has appeared repeatedly in Perspectives, two of which have been devoted primarily to him (Crow 1988, 1990). Fisher’s collected papers are a gold mine, for Fisher often put down his most profound and original ideas in ‘‘throw-away’’ articles, which were published in a five-volume set edited by Henry Bennett (Fisher 1971– 1974). Fisher’s great book (1930) has been reissued in a vari...

Centriole duplication occurs once per cell cycle, ensuring that each cell contains two centrosomes, each containing a mother-daughter pair of tightly engaged centrioles at mitotic entry. Loss of the tight engagement between mother and daughter centrioles appears to license the next round of centriole duplication. However, the molecular mechanisms regulating this process remain largely unknown. ...

The omnipresence of his name and portrait in Bangladesh suggests that Father-of-the-nation Sheikh Mujibur Rahman – known as Bangabandhu is more than just a national hero. He subject secular deification establishes him the fountain political authority an embodiment sovereignty nation one without whom there can be no authority, sovereignty, nation. Historically he was supreme leader movement, ext...

OBJECTIVE Suggested C9orf72 disease mechanisms for amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration include C9orf72 haploinsufficiency, G4C2/C4G2 RNA foci, and dipeptide repeat (DPR) proteins translated from the G4C2 expansion; however, the role of small expansions (e.g., 30-90 repeats) is unknown and was investigated here. METHODS We conducted a molecular and patholo...

all languages have different terms for expressing kinship relations and it seems that beyond these differences one can find similarities in the different systems of kinship terms. morgan (1871) is the first anthropologist who studied kinship systems in different languages and came to this conclusion that kinship systems reflect social systems. mordoch (1949) another anthropologist, distinguishe...