AIM To investigate if iron deposition and fat accumulation in the liver play a pathogenetic role in dimethylnitrosamine (DMN)-induced liver fibrosis in rat. METHODS Thirty rats were treated with DMN at does consecutive days of 10 microL/kg daily, i.p., for 3 consecutive day each week for 4 wk. Rats (n=30) were sacrificed on the first day (model group A) and 21(st) d (model group B) after cess...

The effects of intracranial transforming growth factor (TGF)-beta3 on spontaneous motor activity and energy metabolism were examined in rats. After injection of TGF-beta3 into the cisterna magna of the rat, spontaneous motor activity decreased significantly for 1 h. The intracranial injection of TGF-beta3 produced an immediate decrease in respiratory exchange ratio (RER). No significant changes...

Aspirated fat contains unnecessary components such as water, oil, and blood cells. For better outcomes, tissue purification and condensation are useful, especially when injection volume to the recipient site is limited. Because aspirated fat is relatively poor in adipose-derived stem/stromal cells (ASCs), ASC condensation seems important for obtaining better regeneration and retention. Reducing...

Rats fed a high-fat diet (HFD) present an exaggerated endocrine response to stress conditions, which, like obesity, show a high correlation with cardiovascular diseases. Meanwhile the GABAergic neurotransmission within the dorsomedial hypothalamus (DMH) is involved in the regulation of the physiological responses during emotional stress. Here we evaluated the influence of obesity, induced by a ...

I . Twenty pigs were rcared to a weight of 90 kg on various dietary regimens so that their lipid content varied from 16 to 38%. They were injected intravenously with 400pCi of ‘*KCI. T h e animals were killed 28 h after injection and their contents of water, lipid, sodium and potassium were determined. 2. The specific activity of plasma reached equilibrium 1-12 h after injection, that of urine ...

This study aimed to investigate whether rennin-angiotensin system (RAS) blockade through telmisartan would increase the resistance to streptozotocin- (STZ-) induced diabetes in insulin resistance rats. There were sixty Wistar rats that were divided into four groups: normal control (NC), high-fat diet (HF), high-fat diet plus STZ injection (HF+S), and high-fat diet plus STZ injection and telmisa...

Gravid macaques (n=12) were maintained on a control diet (14% calories from fat, n=4) or a high fat diet (36% calories from fat, n = 8). On gestational day 129, the macaques were injected with ProHance gadolinium contrast for placental imaging (equivalent to the third trimester). Gadolinium dose was varied based on maternal weight, using 0.1 mmol/kg dosing. Fetuses were delivered via cesarean s...

who had sustained fat embolism. For the purposes of the present investigation three blood samples were taken from an arm vein in each patient; the first after the induction of anaesthesia but before insertion of the pertrochanteric needle; the second five minutes after the first injection of contrast material; and the third 20 minutes later. The blood was allowed to clot and the plasma then exa...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : recently autologous fat tissue transfer has gained much popularity. on the other hand, applying the transferring methods with a higher survival rate is still controversial. the aim of this study is to compare dermis-fat graft and dermal-fascia-fat graft. methods : this animal study was conducted in 2008-2009. ...