The objective of the present study is to develop a pharmaceutically stable, cost effective and quality improved robust formulation of Valsartan Immediate Release tablets. The aim of work is related to the formulation and evaluation of 10mg of dispersible tablet. Valsartan belongs to a class of antihypertensive agents called angiotensin II receptor blockers (ARBs). Total nine formulations were p...

In the present work, fast dissolving tablets of granisetron HCl were prepared using low compressible (mannitol) and high compressible saccharides (sorbitol 5-15% w/w) along with crospovidone, croscarmellose sodium and L-HPC as super-disintegrants in different ratios(2-8% w/w) In case of sorbitol, the presence of interlocking crystals that are generated using specific manufacturing conditions en...

Fast dissolving tablets of clonazepam were prepared by sublimation method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of croscarmellose sodium and camphor. Croscarmellose sodium (2-8% w/w) was used as superdisintegrant and camphor (20-40% w/w) was used as subliming agent, to increase ...

The current research work involves preparation of fast dissolving tablets of Aceclofenac by direct compression method using different concentrations of Lepidium sativum mucilage as natural superdisintegrant. A two-factor three-level (3(2)) factorial design is being used to optimize the formulation. Nine formulation batches (D1-D9) were prepared accordingly. Two factors as independent variables ...

tablet formulation (t 16.4 min). Short-term stability studies on the formulation indicated that there are no significant changes in drug 50% content and in vitro dispersion time (p<0.05).

The desire of improved palatability in orally administered products has prompted the development of numerous formulations with improved performance and acceptability. Orally disintegrating tablets are an emerging trend in novel drug delivery system and have received ever-increasing demand during the last few decades. The field has become a rapidly growing area in the pharmaceutical industry and...

The aim of present study was to improve the solubility Rasagilline mesylate, an Atypical Antipsychotic agent which is BCS Class III drug and thus has very low hence poor bioavailability owing less absorption. Moreover mesylate a bitter taste. Thus in attempt made taste mask oral by formulating into solid dispersion then formulate dispersions Fast Dissolving Tablets. Solid Dispersions were formu...

ISSN 14750708 10.2217/THY.09.4 © 2009 Future Medicine Ltd Therapy (2009) 6(3), 407–415 Allergic rhinitis is a major IgE‐mediated chronic respiratory disorder that presents as a complex of nasal, ophthalmic, ear and sinus symptoms such as nasal congestion, nasal itching, rhinor‐ rhea, sneezing and watery/running eyes [1–3]. It is an extremely common condition, which has been estimated to affect ...