A 60-year-old diabetic woman with stage IV chronic kidney disease and a history of lichen planus presented with chronic intermittent solid food dysphagia for seven years that had worsened over the past year. She had associated dyspeptic symptoms with no other gastrointestinal symptoms. She had been treated with lansoprazole and famotidine, with some improvement in her symptoms. She reported no ...

Effects of FRG-8701, a new histamine H2-receptor antagonist, on gastric acid secretion, necrotizing agents-induced gastric lesions and acute gastric or duodenal ulcer in rats were studied. In lumen-perfused rats, intravenous injection of FRG-8701 reduced gastric acid secretion, and its antisecretory effect was almost equipotent to that of famotidine but the duration of action was substantially ...

Purpose: The purpose of the present research was to the effect of camphor as a subliming agent on the mouth dissolving property of famotidine tablets. Method: Orodispersible tablets of famotidine were prepared using camphor as subliming agent and sodium starch glycollate together with crosscarmellose sodium as superdisintegrants. The formulations were evaluated for weight variation, hardness, f...

In this study famotidine was used as a model drug to formulate and evaluate pH-induced in situ gelling system for oral sustained release drug delivery in stomach which has shorter biological half-life. To study the effect of independent variables 3 full factorial design was employed, concentration of pectin as pH dependant polymer and concentration of calcium chloride on dependent variables lik...

A morbidly obese 60-year-old Hispanic woman with chronic obstructive pulmonary disease, renal failure and asthma but no history of skin disease was hospitalized for a putative urinary tract infection. She had developed a red pruritic painless rash 2 days after starting famotidine. She was allergic to ampicillin and had taken dexamethasone, prozac, percocet, diltiazem, theophylline, ciprofloxaci...

Method In this case a premedication protocol of dexamethasone 10 mg + diphenhydramine 50 mg + famotidine 20 mg by mouth were administered 13 hours, 6 hours and 1 hour respectively prior to the infusion of 40 mg of oxaliplatin in 1:10000, 1:1000, 1:100, 1:10 graded dilutions. Each dilution was infused over 1 hour under close telemetry monitoring. A final dilution that contained 90 % of the dose ...

Cystitis is a possible adverse drug reaction associated with the use of tizanidine. Such cases have been rarely reported in literature because of the difficulty in establishing the causality. However, from a pharmacovigilance point of view, it is better to report such cases of a possible association between a drug's use and potential adverse drug reactions. We report a case of a 26-year-old Asi...