نتایج جستجو برای: family history of cancers
تعداد نتایج: 21217780 فیلتر نتایج به سال:
how to cite this article: najafi mr, najafi ma, safaei a. association of family history of epilepsy with earlier age onset of juvenile myoclonic epilepsy. iran j child neurol. spring 2016; 10(2):10-15. abstract objective juvenile myoclonic epilepsy (jme) is supposedly the most frequent subtype of idiopathic generalized epilepsies (ige). the aim of this study was to determine the prevalence of j...
background : this study aimed to compare different body mass index (bmi) categories in individuals with diabetes, prediabetes and normal glucose tolerance among the first degree relatives of type 2 diabetic patients. methods : a cross-sectional study was conducted during 2005-2007 in isfahan, iran. it evaluated 3323 first-degree relatives of diabetic patients selected by consecutive convenient ...
background: individuals with a positive family history of colorectal cancer have an increased risk of developing this type of cancer. the number of affected relatives and the age at diagnosis are two factors that increase the risk of colorectal cancer. the aim of this study was to assess the prevalence of a positive family history of colorectal cancer in a random sample among the iranian genera...
Breast cancer is common in the general population, affecting one woman in every 12. About 5% of breast cancers are caused by dominantly inherited high risk susceptibility mutations in genes such as BRCA1 and BRCA2. Another, larger proportion may be caused by mutations in (as yet) unidentified lower penetrance genes, because even where such high risk mutations are not implicated, a family histor...
BACKGROUND Strong associations between infant vocabulary and school-age language and literacy skills would have important practical and theoretical implications: Preschool assessment of vocabulary skills could be used to identify children at risk of reading and language difficulties, and vocabulary could be viewed as a cognitive foundation for reading. However, evidence to date suggests predict...
Characterization of breast tumors on both estrogen receptor (ER) and progesterone receptor (PR) status suggests distinct biological and clinical profiles. We hypothesized that these tumor subtypes might also show specific differences in their relations with epidemiologic risk factors. Risk factors were assessed via a questionnaire mailed in January 1986 to 37,105 cancer-free women, ages 55-69 y...
Cancer evolves dynamically as clonal expansions supersede one another driven by shifting selective pressures, mutational processes, and disrupted cancer genes. These processes mark the genome, such that a cancer's life history is encrypted in the somatic mutations present. We developed algorithms to decipher this narrative and applied them to 21 breast cancers. Mutational processes evolve acros...
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