نتایج جستجو برای: factor vii
تعداد نتایج: 864410 فیلتر نتایج به سال:
A study was carried out to explore requirements for the inhibition of tissue factor-factor VIIa enzymatic activity in plasma. Reaction mixtures contained plasma, 3H-factor IX or 3H-factor X, tissue factor (vol/vol 2.4% to 24%), and calcium. Tissue factor-factor VIIa activity was evaluated from progress curves of activation of factor IX or factor X, plotted from tritiated activation peptide rele...
In This Issue: • NovoSeven • Therapeutic Interchanges Introduction: Recombinant human activated Factor VII (rFVIIa), or NovoSeven, is a hemostatic agent which is structurally similar to human plasma-derived coagulation Factor VIIa. Recombinant FVIIa is currently licensed by the US Food and Drug Administration (FDA) in patients with hemophilia A or B with inhibitors to Factor VIII or Factor IX o...
Coagulation factors belong to a family of plasma glycosylated proteins that should be activated for appropriate blood coagulation. Congenital deficiencies of these factors cause inheritable hemorrhagic diseases. Factor VII (FVII) deficiency is a rare bleeding disorder with variable clinical symptoms. Various mutations have been identified throughout the F7 gene and can affect all the protein do...
Effect of increasing serum albumin on haemostatic factors synthesized in the liver in CAPD patients.
BACKGROUND This study was performed to evaluate the relationship between serum albumin and plasma concentration of haemostatic factors and the effect of raising serum albumin on haemostatic factors synthesized in the liver in CAPD patients. METHODS We measured blood levels of albumin, fibrinogen, factor II, factor VII, protein C, free protein S, plasminogen, alpha2-antiplasmin and antithrombi...
Recent investigations have suggested that the activation of factor IX by factor VII/tissue factor may be an important alternative route to the generation of factor Xa. Accordingly, we have compared the tissue factor-dependent activation of tritium-labeled factor IX and factor X in a human plasma system and have studied the role of proteases known to stimulate factor VII activity. Plasma was def...
Use of recombinant factor VIIa for hip surgery in a patient with factor-VII deficiency: A case report.
The role of vascular coagulation receptors, particularly modest changes in the levels of these proteins in terms of controlling downstream coagulation factor activation, remains largely unknown. The study reported by Ireland and colleagues in this issue of Arteriosclerosis, Thrombosis, and Vascular Biology1 demonstrates that a moderately common dimorphism in the endothelial cell protein C recep...
جداسازی، کلونینگ و بیان ژن فاکتور VII انعقادی نوترکیب انسانی در رده سلولی CHO راحله حلبیان1، ناصر شاگردی اسماعیلی2، آرزو اوودی2، ناصر مسروری3، دکتر ناصر امیری‌زاده4، دکتر کامران موسوی حسینی5، دکتر احمد قره‌باغیان6، دکتر حوری رضوان7، دکتر محمد علی جلیلی8، دکتر مهریار حبیبی رودکنار9 چکیده سابقه و هدف فاکتور VII ، یک گلیکوپروتئین پلاسمایی است که در آبشار انعقادی تشکیل فیبرین، شرکت دارد....
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