PURPOSE To determine the utility of tear film cytokines as biomarkers for early primary open-angle glaucoma (POAG). METHODS Patients without POAG and eye drop-naïve patients with newly diagnosed POAG were recruited from an academic hospital-based glaucoma practice. Tear films of recruited patients were obtained and analyzed using a multiplex, high-sensitivity electrochemiluminescent enzyme-li...

BACKGROUND We investigated the early efficacy of topical levocabastine, an H(1) histamine-receptor antagonist, in improving the clinical symptoms of allergic conjunctivitis. METHODS Thirty-six patients with allergic conjunctivitis were enrolled. One drop of levocabastine was instilled in one eye and one drop of artificial tears in the contralateral eye. Clinical examinations were performed be...

Case 1 A 51-year-old diabetic visited us for diabetic retinopathy screening. Left eye fundus examination was limited due to asteroid hyalosis (AH) [Fig. 1a]. Optical coherence tomography (OCT) of left eye demonstrated asteroid bodies with posterior vitreous detachment (PVD) [Fig. 1b]. Left eye OCTA revealed multiple black areas in all slabs resembling capillary drop out areas [Fig. 1c-e]. The b...

Static refraction in children after the topical instillation of atropine twice a day during 3.5 days was compared with the refraction after a single instillation of one drop of 0.85% cyclopentolate + 1.5% phenylephrine in a randomized cross-over study. Atropine eye drops were applied by the parents at home, while the combination drop was applied by personnel at the eye clinic. Refraction was de...

Abbreviations: UGH: Uveitis-Glaucoma-Hyphema; IOL: Intraocular Lens; ACIOL: Anterior Chamber Intraocular Lens; PCIOL: Posterior Chamber Intraocular Lens; GCA: Giant Cell Arteritis; NVI: Neovascularization of the Iris; YAG: Yttrium Aluminum Garnet; OD: Right Eye; OS: Left Eye; HbA1c: Hemoglobin A1C; PEE: Punctate Epithelial Erosion; IEI: Illinois Eye Institute; QD: 1 time a day; BID: 2 times a d...

A single-center, open-label study consisting of two visits over the course of approximately 2 weeks was conducted to evaluate the efficacy of Retaine™ ophthalmic emulsion in improving the signs and symptoms of dry eye. Forty-two subjects were enrolled and received 1-2 drops twice daily of Retaine™ beginning at the first visit (day 1) and ending at the second visit. Subjects were instructed to c...