BACKGROUND Extubation failure can result from poor respiratory drive, impaired respiratory muscle function, or excessive inspiratory load. Measurement of airway pressure changes either during tidal breathing or after end-expiratory occlusion allows assessment of respiratory drive and muscle function. OBJECTIVE To determine whether the results of airway pressure measurements characterized chil...

BACKGROUND Risk factors of delayed extubation, prolonged intensive care unit (ICU) length of stay (LOS), and mortality have not been studied for patients administered fast-track cardiac anesthesia (FTCA). The authors' goals were to determine risk factors of outcomes and cardiac risk scores (CRS) for CABG patients undergoing FTCA. METHODS Consecutive CABG patients undergoing FTCA were prospect...

Objective The purpose of this study was to compare the efficacy of continuous low pressure support (PSV) and T-piece as strategies for discontinuation of mechanical ventilation and extubation in a surgical ICU. Patients and Methods This was a prospective open label randomized control study in surgical ICU patients who were intubated, mechanically ventilated, and who met criteria for a spontan...

OBJECTIVE Neonates mechanic ventilation weaning has become a major clinical challenge, and constitutes a large portion of neonatal intensive care units workload. The spontaneous breathing trial (SBT), performed immediately before extubation, can provide useful information on the patient's spontaneous breathing ability. This study aimed to assess the SBT effectiveness for extubation success pred...

BACKGROUND Assessment of a patient's readiness for removal of the endotracheal tube in the ICU is based on respiratory, airway, and neurological measures. However, nearly 20% of patients require reintubation. We created a prediction model for the need for reintubation, which incorporates variables importantly contributing to extubation failure. METHODS This was a cohort study of 2,007 endotra...

OBJECTIVE Despite the use of spontaneous breathing trial (SBT), predicting weaning success remains a major clinical challenge. Because cardiovascular dysfunction could be a major underlying mechanism of weaning failure, we evaluated the role of the levels of B-type natriuretic peptide (BNP), a marker for cardiovascular function, in patients who passed a 2-hr SBT. DESIGN, SETTING, AND PATIENTS...

Objective: To evaluate the efficacy of midazolam and propofol for postoperative sedation early extubation following cardiac surgery. Methods: This randomized control trial was conducted at Cardiac Surgery Department Choudhary Pervaiz Elahi Institute Cardiology from February 2019 to 2020. A total 60 American Society Anesthesiologists (ASA) III patients planned undergo coronary artery bypass graf...

Background The mid-sternum is the main source of pain after open cardiac surgery. aim this study was to investigate effect bilateral transversus thoracis muscle plane (TTMP) blocks on Methods Sixty patients were randomly divided into two groups: TTMP (TP group) or no nerve block (CO group). primary endpoint perioperative sufentanil consumption. secondary outcome measures included postoperative ...

Methods A historical cohort study was conducted in a mixed intensive care unit with 40 beds at a University Centre. Patients analyzed were those admitted between 2010 and 2014, over the age of 16 years, with invasive mechanical ventilation for more than 24 hours and who overcome a spontaneous breath testing (SBT). Predictive variables: age, gender, days of intubation, length of intravenous seda...

Sixty infants (median gestational age 29 weeks) with acute and 60 infants (median gestational age 25 weeks) with chronic respiratory distress were randomised to be extubated either directly into a headbox or onto 3 cm H2O nasal continuous positive airway pressure (CPAP). Our aim was to test the hypothesis that extubation onto nasal CPAP rather than directly into a headbox was more likely to be ...