نتایج جستجو برای: expression network
تعداد نتایج: 1516065 فیلتر نتایج به سال:
Biological networks may be categorised [1] as metabolic pathways, signal transduction pathways, gene regulatory networks and protein-protein interaction (PPI). A Gene Regulatory Network (GRN) is a collection of genes in a cell which interact with each other and with other molecules in the cell such as proteins or metabolites, thereby governing the rates at which genes in the network are transcr...
Background: Transforming growth factor (TGF)-β is over-expressed in a wide variety of cancers such as lung adenocarcinoma. TGF-β plays a major role in cancer progression through regulating cancer cell proliferation and remodeling of the tumor micro-environment. However, it is still a great challenge to explain the phenotypic effects caused by TGF-β stimulation and the effect of TGF-β stimulatio...
Ordinary differential equations (ODE) have been widely used for modeling and analysis of dynamic gene networks in systems biology. In this paper, we propose an optimization method that can infer a gene regulatory network from time-series gene expression data. Specifically, the following four cases are considered: (1) reconstruction of a gene network from synthetic gene expression data with nois...
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