Leucine-rich nuclear export signals (NESs) are recognized by the NES receptor exportin 1 and are central to the export of multiple shuttling proteins and RNAs. The export of messenger RNA in vertebrates was, however, thought to occur by a different pathway, because inhibition by injection of a synthetic Rev NES conjugate could not be demonstrated. Here we find that peptide conjugates composed o...

Participation in global trade means that China’s vegetables and fruits industry faces international food safety standards and increased scrutiny worldwide. The objectives of this paper were to investigate how existing food safety standards and regulations in the importing countries impact the export of vegetables and fruits from China. This paper discussed the current and historical situations ...

The export of messenger RNAs (mRNAs) is the final of several nuclear posttranscriptional steps of gene expression. The formation of export-competent mRNPs involves the recruitment of export factors that are assumed to facilitate transport of the mature mRNAs. Using in vitro splicing assays, we show that a core set of export factors, including ALYREF, UAP56 and DDX39, readily associate with the ...

We have studied the export kinetics of the maltose-binding protein (MBP) of Escherichia coli, the malE gene product, when it is synthesized with either a wildtype signal sequence or with a mutationally altered signal sequence that affects the efficiency of secretion to the periplasm. Our results confirm a very rapid export process for the wild-type protein and, in contrast, reveal a relatively ...

In eukaryotic cells, nuclear export of nascent ribosomal subunits through the nuclear pore complex depends on the small GTPase Ran. However, neither the nuclear export signals (NESs) for the ribosomal subunits nor the receptor proteins, which recognize the NESs and mediate export of the subunits, have been identified. We showed previously that Nmd3p is an essential protein from yeast that is re...

this study investigated the export status of stone fruits in iran during 1997 to 2010.export trends and revealed comparative advantage of indices, namely, revealedcomparative advantage (rca), revealed symmetric comparative advantage (rsca),and relative export advantage (rxa) as well as trade mapping (tm) were investigatedfor cherries, plums, peaches, and apricots. target markets for these produ...

Private standards are increasingly governing international food trade, but little is known about the implications for developing countries. The objective of the study is to provide evidence in the ongoing debate on standards as barrier or catalyst for developing countries’ export. We use the Peruvian fresh asparagus export sector as a case study and provide empirical panel data evidence on the ...

Peptides and misfolded secretory proteins are transported efficiently from the endoplasmic reticulum (ER) lumen to the cytosol, where the proteins are degraded by proteasomes. Protein export depends on Sec61p, the ribosome-binding core component of the protein translocation channel in the ER membrane. We found that prebinding of ribosomes abolished export of a glycopeptide from yeast microsomes...

Nuclear export of messenger ribonucleoproteins (mRNPs) through the nuclear pore complex (NPC) can be roughly classified into two forms: bulk and specific export, involving an nuclear RNA export factor 1 (NXF1)-dependent pathway and chromosome region maintenance 1 (CRM1)-dependent pathway, respectively. SUN proteins constitute the inner nuclear envelope component of the l I: nker of N: ucleoskel...