Magyar, Clara E., Kenneth E. White, Raul Rojas, Gerard Apodaca, and Peter A. Friedman. Plasma membrane Ca2 -ATPase and NCX1 Na /Ca2 exchanger expression in distal convoluted tubule cells. Am J Physiol Renal Physiol 283: F29–F40, 2002; 10.1152/ajprenal.00252.2000.— The plasma membrane Ca2 -ATPase (PMCA) and the NCX1 Na /Ca2 exchanger regulate intracellular Ca2 concentrations and mediate Ca2 effl...

The objective of this paper is to evaluate and optimize the performance of 1 kW integrated heat exchanger module for new generations of air cooled heat exchangers. The first objective is to minimize the ratio of the header frontal area to the entire heat exchanger frontal which will help to reduce the header size. The second objective is to minimize the pressure drop for the entire heat exchang...

Mechanisms of intracellular pH (pHi) regulation were investigated in anoxia-tolerant hepatocytes from goldfish Carassius auratus, and compared to the situation in the anoxia-intolerant hepatocytes from trout Oncorhynchus mykiss. Under normoxic conditions, the pHi of goldfish hepatocytes was regulated by a Na(+)/H(+) exchanger and a Na(+)-independent Cl(-)/HCO(3)(-) exchanger, the latter being a...

Our study aimed to assess a possible functional role of the Na(+)/Ca(2+) exchanger in the regulation of renal vascular resistance (RVR). Therefore, we investigated the effects of an inhibition of the Na(+)/Ca(2+) exchanger either by lowering the extracellular sodium concentration ([Na(+)](e)) or, pharmacologically on RVR, by using isolated perfused rat kidneys. Graded decreases in [Na(+)](e) le...

Flash tank evaporation combined with a condensing heat exchanger can be used when heat exchange is required between two streams and where at least one of these streams is difficult to handle (in terms of solid particles content, viscosity, pH, consistency etc.). To increase the efficiency of heat exchange, a cascade of these units in series can be used. Heat transfer relationships in such a cas...

www.chestpubs.org our data clearly show that patients with CLD undergoing major hepatic resection fall under a high-risk designation. With the decision to use prophylactic methods against VTE frequently predicated on an assessment of individual patient risk, this information may prove valuable when used in conjunction with the American College of Chest Physicians’ Evidence-Based Clinical Practi...

Inhibition of the sodium-hydrogen exchanger (NHE) is a powerful experimental tool to inhibit sodium and calcium accumulation within the ischemic myocyte and halt progression of cell ischemia to cell necrosis. This paper describes the protocol and rationale of a first large-scale clinical trial designed to evaluate the safety and efficacy of cariporide, a novel specific and potent inhibitor of t...

We demonstrated previously that Na+/H+ exchange activity was enhanced in rat parotid acinar cells following muscarinic (carbachol) or alpha-adrenergic (epinephrine) stimulation and that this activation of the exchanger was preserved in plasma membrane vesicles prepared from these cells (Manganel, M., and Turner, R. J. (1989) J. Membr. Biol. 111, 191-198). The carbachol dose dependence of this e...

The paper deals with the block-oriented approach in modelling of a solar domestic hot water system. Due to the linking possibility to other technological processes (greenhouse, dryer, etc.) the Matlab+Simulink software was decided to use. The entire model consists of the sub-system models as collector, heat exchanger and storage tank. The governing heat and mass transfer equations are given alo...