Central MessageAdaptions of current EVLP protocols are needed to be able perfuse donor lungs for 24 hours and longer.See Article page 1963. Adaptions longer. See A great potential ex vivo lung perfusion (EVLP) lies in reconditioning grafts an unacceptable quality so that they can used transplantation. In this regard, several approaches have been described experimental studies, including the tre...

BACKGROUND In the present study, a technique for computer-assisted, normothermic, oxygenated, ex vivo, recirculating small bowel perfusion was established as a tool to investigate organ pretreatment protocols and ischemia/reperfusion phenomena. A prerequisite for the desired setup was an organ chamber for ex vivo perfusion and the use of syngeneic whole blood as perfusate. METHODS The entire ...

Central MessageNew strategies in ex vivo lung perfusion extend preservation to 24 hours—an achievement that will enable surgeons better allocate, evaluate, rehabilitate, and eventually enhance allografts.See Article page 1963. New allografts. See In clinical transplantation, (EVLP) offers 3 critical advantages over conventional methods. First, allografts, which reproducibly tolerate a limited t...