The zebrafish is a model organism for studies of vertebrate muscle differentiation and development. However, an understanding of fish muscle physiology during this period is limited. We examined the membrane, contractile, electrical coupling, and synaptic properties of embryonic red (ER) and white (EW) muscle fibers in developing zebrafish from 1 to 5 days postfertilization. Resting membrane po...

BACKGROUND AND OBJECTIVE The mechanism inducing either inflammation or tolerance to orally administered food allergens remains unclear. To investigate this we analyzed mouse models of food allergy (OVA23-3) and tolerance (DO11.10 [D10]), both of which express ovalbumin (OVA)-specific T-cell receptors. METHODS OVA23-3, recombination activating gene (RAG)-2-deficient OVA23-3 (R23-3), D10, and R...

It is shown that Einstein–Weyl (EW) equations in 2+1 dimensions contain the dispersionless Kadomtsev–Petviashvili (dKP) equation as a special case: If an EW structure admits a constant weighted vector then it is locally given by h = dy2−4dxdt−4udt2, ν = −4uxdt, where u = u(x, y, t) satisfies the dKP equation (ut − uux)x = uyy. Linearised solutions to the dKP equation are shown to give rise to f...

Numerical simulations of the intergalactic medium have shown that at the present epoch a significant fraction (40−50%) of the baryonic component should be found in the (T ∼ 10K) Warm-Hot Intergalactic Medium (WHIM) with several recent observational lines of evidence indicating the validity of the prediction. We here recompute the evolution of the WHIM with the following major improvements: (1) ...

This paper presents a preprocessing technique based on exponential windowing (EW) for parameter estimation of superimposed exponentially damped sinusoids. It is shown that the EW technique significantly improves the robustness to noise over two other commonly used preprocessing techniques: subspace decomposition and higher order statistics. An ad-hoc but efficient approach for the EW parameter ...

BACKGROUND At diagnosis, identification of reliable biological indicators of prognosis to allow stratification of patients according to different risks is an important but still unresolved aspect in the treatment of Ewing sarcoma (EWS) patients. This study aimed to explore the role of miR-34A expression on prognosis of EWS patients. PATIENTS AND METHODS Specimens from 109 patients with non-me...

PURPOSE/OBJECTIVES To evaluate the effects of expressive writing (EW) interventions in patients with cancer.
. DATA SOURCES Electronic databases searched included both international and Korean databases through January 2015.
. DATA SYNTHESIS Of the 20 trials that met the eligibility criteria of this review, a meta-analysis was conducted of 14 articles involving 13 randomized and 1 nonrandom...

Identifying and characterizing brain regions regulating alcohol consumption is beneficial for understanding the mechanisms of alcoholism. To this aim, we first identified brain regions changing in expression of the inducible transcription factor c-Fos in the alcohol-preferring C57BL/6J (B6) and alcohol-avoiding DBA/2J (D2) mice after ethanol consumption. Drinking a 5% ethanol/10% sucrose soluti...

Electromechanical wave imaging (EWI) has been show capable of directly and entirely non-invasively mapping the trans mural electromechanical activation in all four cardiac chambers in vivo. In this study, we assessed EWI repeatability and reproducibility, as well as its capability of localizing electronic and, for the first time, biological pacing locations in closed-chest, conscious canines. E...