Objective(s):Organic anion transporter polypeptide 1B1 (OATP1B1) encoded by solute carrier organic transporter 1B1 (SLCO1B1) gene; a transporter involved in the uptake of drugs and endogenous compounds is present in hepatocyte sinusoidal membrane. Aim of this study was to investigate the frequencies of functionally significant SNPs (388A>G and 521T>C) and their haplotypes in 6 ethnic groups of ...

CYP2C19 polymorphism is associated with pretreatment drug response prediction, metabolism, and disposition. Pakistan consists of a population comprising of various ethnic groups residing in different regions of the country each claiming diverse ethnic origins. The identification of CYP450 genotypic composition of these populations is therefore necessary to avoid adverse drug reactions in these ...

Social development undoubtedly requires people participation in different domains. It seems without participation, we cannot achieve a people-centered, inclusive and sustainable social development. In the social development process, all citizens with various ethnic and religious interests are able to affect on all the social phenomena and variables, based on their competencies and mental capaci...

It becomes the important issue for the medical supplies administration to solve the drug lag in our country. As means to overcome both the slow speed and high cost of clinical trial for new drug application in Japan, it seems useful to carry out clinical development simultaneously in East Asia countries such as China, Korea and Taiwan where it is thought that each country has similar ethnicity ...

abstract background and purpose: overweight and obesity are the health problem in adolescents and the main purpose of this study was to evaluate this problem and some socio-demographicrelated factors among two ethnic groups in iranian northern primary school children in 2010. materials and methods: this was a descriptive and cross-sectional study that performed on 4165 students (turkman = 2852a...

Immigrants to the United States face rejection from other Americans on the basis of their ethnic group membership. Among members of ethnic minority groups who were born in the United States, rejection is tied to higher ethnic identification and less positive attitudes toward the national majority. Relatively little research has examined this relationship among first-generation immigrants (i.e.,...

Ethnically diverse settings provide opportunities for interethnic friendship but can also increase the preference for same-ethnic friendship. Therefore, same-ethnic friendship preferences, or ethnic homophily, can work at cross-purposes with policy recommendations to diversify ethnic representation in social settings. In order to effectively overcome ethnic segregation, we need to identify thos...

Background: Human leukocyte antigens (HLA) are polymorphic cell surface proteins. Distribution of HLA alleles vary among different racial and ethnic populations in unrelated stem cell registries. Determination of HLA allele frequencies in different ethnic groups is useful for population genetic analyses. Materials and Methods: Based on data available from the Iranian Stem Cell Donor Registry...

This study examined the association between 3 components of ethnic identity (exploration, resolution, and affirmation) and factors related to family, neighborhood, and individual characteristics. The purpose was to identity factors that are positively associated with adolescent ethnic identity among a sample of 187 Latino adolescents with a mean age of 14.61. The findings suggested that family ...