نتایج جستجو برای: est و چرخهی ppar

تعداد نتایج: 795319  

2006
Guang-Hui Liu Jing Qu Xun Shen William Tansey

PPAR , a member of the nuclear receptor superfamily, and thioredoxin, a critical redox-regulator in cells, were found to form a negative feedback loop, which autoregulates transcriptional activity of PPAR . Thioredoxin was identified as a target gene of PPAR . Activation of PPAR leads to increase of thioredoxin expression as well as its translocation from cytoplasm to nucleus, whereas ectopic o...

2009
Mohd Ashraf Ganie Abdul Hamid Zargar

There are three peroxisome proliferator-activated receptors (PPARs) subtypes which are commonly designated PPAR alpha, PPAR gamma and PPAR beta/delta. PPAR alpha activation increases high density lipoprotein (HDL) cholesterol synthesis, stimulates “reverse” cholesterol transport and reduces triglycerides. PPAR gamma activation results in insulin sensitization and antidiabetic action. Combined t...

Journal: :Circulation research 2001
D P Kelly

The peroxisome proliferator-activated receptors (PPARs) are a family of ligand-activated transcription factors within the broad nuclear receptor superfamily. Recent evidence indicates that the PPARs play critical regulatory roles in a variety of biologic processes relevant to the heart and vasculature including lipid and energy metabolism, inflammation, and cellular differentiation (reviewed in...

2008
Iman M. Ahmad Maher Y. Abdalla Noor H. Mustafa Esam Y. Qnais Fuad A. Abdulla

صخلملا This study was designed to evaluate the cytotoxic effect ةتبن قارولأ يئاملا صلختسملا ةيمس ىدم ميقتل ةساردلا هذه تممص ايلاخ ضر MDA-MB231 و FaDu ةدملل ةيناطرسلا ايلاخلا ةجلا يف تابارطضاب صلختسملا اذهب لختسم ص ملا ةتبن قارولأ يئا © 2009 Jordan Journal of Biological Sciences. All rights reserved

2004
Daniel Kelly Nikolaus Marx Hélène Duez Jean-Charles Fruchart Bart Staels

A large body of data gathered over the past couple of years has identified the peroxisome proliferator-activated receptors (PPAR) , , and / as transcription factors exerting modulatory actions in vascular cells. PPARs, which belong to the nuclear receptor family of ligand-activated transcription factors, were originally described as gene regulators of various metabolic pathways. Although the PP...

Journal: :Molecular pharmacology 2008
Salvatore Cuzzocrea Stefano Bruscoli Emanuela Mazzon Concetta Crisafulli Valerio Donato Rosanna Di Paola Enrico Velardi Emanuela Esposito Giuseppe Nocentini Carlo Riccardi

Glucocorticoids (GCs) are effective anti-inflammatory agents widely used in the therapeutic approach to treatment of acute and chronic inflammatory diseases. Previous results suggest that peroxisome proliferator-activated receptor-alpha (PPAR-alpha), an intracellular transcription factor activated by fatty acids, plays a role in the control of inflammation. With the aim of characterizing the ro...

2012
Teresa Ramirez Ming Tong Carol A. Ayala Paul R. Monfils Paul N. McMillan Valerie Zabala Jack R. Wands Suzanne M. de la Monte

Chronic alcoholic liver disease is associated with hepatic insulin resistance, inflammation, oxidative and ER stress, mitochondrial dysfunction, and DNA damage. Peroxisome-proliferator activated receptor (PPAR) agonists are insulin sensitizers that have anti-inflammatory/anti-oxidant effects. We previously showed that PPAR agonists can restore hepatic insulin responsiveness in chronic ethanol-f...

Journal: :Cardiovascular Diabetology 2005
Alexander Tenenbaum Michael Motro Enrique Z Fisman

There are three peroxisome proliferator-activated receptors (PPARs) subtypes which are commonly designated PPAR alpha, PPAR gamma and PPAR beta/delta. PPAR alpha activation increases high density lipoprotein (HDL) cholesterol synthesis, stimulates "reverse" cholesterol transport and reduces triglycerides. PPAR gamma activation results in insulin sensitization and antidiabetic action. Until rece...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد تهران مرکزی - دانشکده زبانهای خارجی 1391

théoriquement, lenseignement constitue, dans la relation didactique, un pôle symétrique à celui de lapprentissage. du point de vue du curriculum, lenseignement est généralement caractérisé comme le moyen par lequel le curriculum est mis en oeuvre. les progrès dans les connaissances psychologiques sur les phénomènes dappropriation ont montré quun savoir est véritablement approprié, cest-à-d...

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