Using a theorem prover, we have veriied a microprocessor design, FM9801. We deene our correctness criterion for processors with speculative execution and interrupts. Our veriication approach deenes an invariant on an intermediate abstraction that records the history of instructions. We veriied the invariant rst, and then proved the correct-ness criterion. We found several bugs during the veriic...

Background The indiscriminate use of antibiotics has caused bacteria to develop mechanisms of resistance to antibacterial agents, limiting treatment options. Therefore, there is a great need for alternative methods to control infections, especially those related to skin. One of the alternative methods is the high frequency equipment (HFE), which is used on skin conditions as an analgesic, an an...

AIM To determine the normal SpO2 in healthy term newborns at mild altitude (MA, 780 metres) compared with sea level (SL), within the context of universal screening for critical congenital heart disease (CCHD). METHODS We studied 199 (119 at MA and 80 at SL) consecutively born healthy newborns. SpO2 recordings were at 24-72 h using Masimo SET Radical-7 on the right hand and left foot. RESULT...

Objectives:  Methamphetamine (MA) use disorder is a new health problem among Iranian female methadone patients that need special treatment and rehabilitation services. However, there are few studies describing their baseline characteristics, their reasons for MA use while in treatment and their treatment needs and success. The study aimed to investigate these research gaps. Methods: Participan...

a b s t r a c tintroduction: the nucleus cuneiformis (ncf) and ventrolateral periaqueductal gray (vlpag), two adjacent areas, mediate the central pain modulation and project to the nucleus raphe magnus (nrm). methods: this study examined whether the antinociceptive effect of morphine microinjected into the ncf is influenced by inactivation of vlpag and nrm in rats. animals were bilaterally micr...

Methamphetamine (MA) abuse is a major public health and safety concern throughout the world and a growing burden on healthcare costs. The purpose of the present study was to investigate the protective effect of fluoxetine against MA‑induced chronic pulmonary inflammation and to evaluate the potential role of nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated antioxidative stress. Wista...

Targeting of plasminogen activators to the fibrin component of a thrombus with the use of monoclonal antibodies (MA) directed against human fibrin may enhance their thrombolytic potency and fibrin-specificity. The thrombolytic and pharmacokinetic properties of rscu-PA/MA-FU1-74, an immunoconjugate of recombinant single-chain urokinase-type plasminogen activator (rscu-PA) and a bispecific MA dir...

We analyzed phylogeographic patterns in the western spotted skunk, Spilogale gracilis Merriam, 1890 (Carnivora: Mephitidae) in relation to historical events associated with Pre-Pleistocene Divergence (PPD) and Quaternary climate change (QCC) using mitochondrial DNA from 97 individuals distributed across Western North America. Divergence times were generated using BEAST to estimate when isolatio...

Background: The oncologic behavior of mucinous adenocarcinoma (MA) of colorectal differs from non-mucinous adenocarcinoma (NMA). MA is more advanced at diagnosis and has a poorer prognosis than NMA. We aimed to evaluate prognostic factors and survival rate in patients with MA compared with NMA in Western Iran. Methods: During 2008-2015 in a retrospective study, 83 patients with CRC referred to...