Introduction:  Esophageal atresia is one of the most significant congenital diseases in pediatric surgery. Postoperative complications have become an important issue. Additionally, the little data are about life quality of baby's that had been surgery. The aim of our study was to analyze and evaluating the long- term life quality of subjects. Methods: We performed an observational study of the...

Objective(s): Ranking as the sixth commonest cancer, esophageal squamous cell carcinoma (ESCC) represents one of the leading causes of cancer death worldwide. One of the main reasons for the low survival of patients with esophageal cancer is its late diagnosis. Materials and Methods: We used proteomics approach to analyze ESCC tissues with the aim of a better understanding of the malignant mech...

Background and Objective: Serine and glycine are connecting lines for biosynthesis and are essential resources for synthesis of proteins, nucleic acids and lipids that are necessary for cancer cell growth. The purpose of this study was to set a comparison of serine and glycine in patients with esophageal cancer and in healthy people. Materials and Methods: 37 plasma samples were collected from...

Ovarian sex cord-stromal tumors are relatively infrequent neoplasms that account for approximately 8% of all primary ovarian neoplasm. Sex cord-stromal tumors of the ovary include granulosa cell tumors, fibrothecomas, Sertoli-Leydigcell tumors, steroid cell tumors, and sclerosing stromal tumors (SST). Sclerosing stromal tumors account for 2% to 6% of ovarian stromal tumors. Despite the rarity o...

BACKGROUND/AIMS Achalasia is a primary motility disorder of esophagus. Many parameters represent esophageal function and morphologic changes, but their interrelationship is not yet established. We hypothesized that esophageal body would need to generate unusual pressure to empty the food bolus through the non-relaxing lower esophageal sphincter in patients with achalasia; therefore, higher is t...

500 cases of Esophago-Gastroscopy were evaluated at the Shahid Moddares teaching and research medical center. Endoscopic diagnosis were:  38% Gastritis, 24% Duodenal Ulcer, 8% Esophageal Carcinoma, 6% Gastric Carcinoma, 6% Gastric Ulcer, 6% Hiatal Hernia, 3% Esophageal Varises.  In 68% of these cases Gastroscopy findings were in Agreement with Radiology reports. 

Introduction: Caustic ingestion is responsible for a spectrum of upper gastrointestinal tract injury from self-limited to perforation. This study conducted to evaluate clinical characteristics as well as surgical outcomes in patients with caustic ingestion.   Materials and Methods: Between Nov1993 to march 2011, 14 adults with a clinical evidence of corrosive ingestion were admitted into our in...

BACKGROUND AND AIMS: Because of the extremely low neoplastic progression rate in Barrett's esophagus, it is difficult to diagnose patients with concomitant adenocarcinoma early in their disease course. If biomarkers existed in normal squamous esophageal epithelium to identify patients with concomitant esophageal adenocarcinoma, potential applications would be far-reaching. The aim of the curren...

IMPORTANCE A rare variant of mucous membrane pemphigoid (MMP) is characterized by circulating anti-laminin 332 (Lam332) autoantibodies and seems to be associated with concurrent malignant neoplasms. OBJECTIVE To determine the prevalence and clinical significance of anti-Lam332 autoantibody detection from a large series of patients with MMP. DESIGN Multicenter retrospective study. SETTING ...