BACKGROUND Achalasia is a primary esophageal motor disorder involving the body of the esophagus and lower esophageal sphincter. The mechanism is destruction of the myenteric plexus after a viral infection. Multiple methods of treatment with variable results induced in achalasia. MATERIALS AND METHODS We analyzed 70 patients with achalasia that underwent surgical treatment with transabdominal ...

INTRODUCTION Achalasia cardia is characterized by failure of the lower esophageal sphincter to relax in response to swallowing and by an absence of peristalsis in the esophageal body. Absence of a gastric air bubble is a well known radiological finding. Pneumatic balloon dilatation results in reappearance of the gastric bubble. CASE PRESENTATION We report the case of a 43-year-old Indian man ...

A 34-year-old man was referred to our hospital because of chest pain and dysphagia that had lasted for 5 years. Endoscopy showed a tight esophagogastric junction (●" Fig.1). On high resolution manometry (Star Medical, Tokyo, Japan), the mean lower esophageal sphincter (LES) pressure and integrated relaxation pressure were 44.3 and 43.3mmHg, respectively (●" Fig.2). Type II achalasia was diagnos...

BACKGROUND/AIMS Per-oral endoscopic myotomy (POEM) is a new minimally invasive technique to treat achalasia. METHODS We performed a review of the literature of POEM with a special focus on technical details and the results obtained with this technique in patients with achalasia and other esophageal motility disorders. RESULTS Thousands of POEM procedures have been performed worldwide since ...

Abstract Background and aim Esophago-gastric junction outflow obstruction (EGJOO) is a relatively new clinical entity revealed by high-resolution manometry (HRM) that can have two different etiologies, i.e. idiopathic or secondary (esophageal strictures, eosinophilic esophagitis, giant hiatal hernia, prior fundoplication bariatric surgery, malignancy). Treatment of EGJOO currently mirrors achal...

TO THE EDITOR: I read with great interest the paper entitled “Achalasia cardia subtyping by high-resolution manometry predicts the therapeutic outcome of pneumatic balloon dilatation” by Pratap et al, which was published in January 2011 issue of Journal of Neurogastroenterology and Motility. Achalasia is the best known primary esophageal motility disorder characterized by absent peristalsis of ...

Epidemiology Most studies that evaluate the epidemiology of achalasia are retrospective. Studies on he incidence and prevalence of achalasia come mostly rom the United Kingdom, but there have been also tudies of diverse populations such as Northern Europe, srael, New Zealand, the United States, and Zimbabwe.1–5 hese studies indicate that the incidence is approxiately 1 in 100,000 individuals an...

The most common and challenging gastrointestinal motility disorders in children include gastroesophageal reflux disease (GERD), esophageal achalasia, gastroparesis, chronic intestinal pseudo-obstruction, and constipation. GERD is the most common gastrointestinal motility disorder affecting children and is diagnosed clinically and treated primarily with acid secretion blockade. Esophageal achala...

Achalasia is characterized by loss of coordinated esophageal peristalsis and failure of the lower esophageal sphincter (LES) to completely relax. High resolution manometry distinguishes three subtypes [1, 2]. The Eckardt score evaluates clinical symptoms, but not quality of life [3]. The treatment aim is to decrease the LES pressure and the integrated relaxation pressure (IRP), in order to impr...

During the 1970s and the 1980s, operations for benign esophageal disorders were often withheld or delayed in favor of less effective forms of treatment in an effort to prevent the postoperative discomfort, the long hospital stay, and the recovery time associated with open surgical procedures. For instance, pneumatic dilatation became first-line therapy for achalasia, even though surgical manage...