BACKGROUND Since ancient times, various infectious diseases have been treated using herbal drugs. Today, efforts regarding the discovery of the effectual components of plants possessing antimicrobial properties are advanced. Herbal essential oils are widely used for treatment of various diseases, and they play an important role in health care considerations. METHODS The antibacterial activity...

Esmaeili A., Rohany S., Safaiyan S., Amir Z.S. (2011): Microbial transformation of citral by Aspergillus niger-PTCC 5011 and study of the pathways involved. Czech J. Food Sci., 29: 610–615. Citronellol and hydroxy citronellal are fragrance ingredients used in decorative cosmetics and fine fragrances. They have many applications in flavourings, extracts, foods, and drugs manufacturing. Their use...

F18 fimbrial Esherichia coli strains are associated with porcine postweaning diarrhea and pig edema disease. Recently, the FedF subunit was identified as the adhesin of the F18 fimbriae. In this study, adhesion domains of FedF were further studied by constructing deletions within the fedF gene and expressing FedF proteins with deletions either together with the other F18 fimbrial subunits or as...

herbs have been used for its medicinal properties from several thousand years ago. herbs, essences and extracts, possess a variety level of biological activities and antimicrobial activities of a large number of them have been proved. eucalyptus is one of these plants which the anti-virus effects of its extract has long been used to treat influenza and colds in most parts of the world. the aim ...

In the present investigation, a gene encoding extracellular lipase was cloned from a Bacillus licheniformis. The recombinant protein containing His-tag was expressed as inclusion bodies in Esherichia coli BL21DE3 cells, using pET-23a as expression vector. Expressed protein purified from the inclusion bodies demonstrated ~22 kDa protein band on 12 % SDS-PAGE. It exhibited specific activity of 0....

Live-cell imaging by light microscopy has demonstrated that all cells are spatially and temporally organized. Quantitative, computational image analysis is an important part of cellular imaging, providing both enriched information about individual cell properties and the ability to analyze large datasets. However, such studies are often limited by the small size and variable shape of objects of...

Gene-mediated enzyme prodrug therapy (GDEPT) seeks to increase the therapeutic index of anti-neoplastic agents by promoting selective activation of relatively nontoxic drug derivatives at sites of specific enzyme expression. Glucuronide prodrugs are attractive for GDEPT due to their low toxicity, bystander effect in the interstitial tumor space and the large range of possible glucuronide drug t...

In this study, cDNA encoding the Camelus dromedarius lactoferrin (cLf) was isolated from mammary gland by reverse transcription polymerase chain reaction and cloned to the pART27 expression vector. Its predicted amino acid sequence was analyzed and compared with lactoferrin of other mammalian species. Secondary and tertiary structures were predicted and modeled by online tools. Then cLf cDNA wa...

Baobab (Adansonia digitata L.) is known in Africa as the tree of life because there are many traditional uses for every part of it, from the leaves to the roots. This study carried out the proximate analysis of baobab leaves, screened the phytochemicals present and determined the leaves’ aqueous extract antimicrobial activity to suit the traditional way of preparation and use. Phytochemicals sc...